If you smoke before you eat a cookie it will not ruin anything. You will definately feel the difference between smoking and eating. The cookie will demand all the attention. When I eat them there is no way I feel like smoking while it lasts. Smoking before you eat one of these is like getting on a plane and then have the space shuttle take off from the plane with you on it. Will you notice that you are no longer on the plane and zooming around in space? Hell yeah!