SweetSue's Cannabis Oil Study Hall

[SweetSue]

Question: lecithin and liposomal encapsulation

Somewhere in this gargantuan forum I remember reading about using lecithin to improve the bioavailability of the cannabinoids in cannabis oil. Here, or elsewhere, I have seen two methods described: one involves mixing liquid lecithin with CO and its carrier and storing the mixture in the fridge for a few months before it's ready; the other method involves heating the mix for 30-60 minutes and then it's good to use as soon as it's cooled.

Could someone kindly direct me into a thread where I can see the recommended method & recipe here, please?

I find that liquid lecithin is almost unattainable where I live (Australia), though it is easy to find granulated lecithin derived from soy or from eggs. If you are not vegan, does it matter where it originates?

Thanks!

It is one of those sticking points that the drying process strips the lecithin of an important component. I detest these types of dilemmas and the frustration that arises. In this case, I consider the lecithin in the eggs I cook with to be a bonus to the intended bioavailability. If you have access to a powdered lecithin made from eggs I might be very comfortable with that. Eggs are my favorite protein source. The eggs added with the brownie mix don't encapsulate the cannabinoids in the same manner the refrigeration does.

That refrigeration needs to be at least six hours. I'm not familiar with the months needed before use. Grow Goddess has a technique for production of concentrated oil without heat that requires months to decarb, but the addition of lecithin and a carrier oil is typically done as you prepare the CCO for administration, as in making capsules and suppositories. Those can be stored for months in the refrigerator.

It is a gargantuan forum, and we encourage questions to save you the frustration of trying to wade your way through what we've already seen. In here we brainstorm, so we stay fairly current. Please, keep asking.

As KR pointed out, soy products need to be verified GMO. We have enough challenges with the gut flora in our current world. No reason to complicate the matter.

 

[SweetSue]

So a little update on my oil making. I am going to make RSO (Rick Simpson Oil) most of you already know what it is. I bought good 5 liter Isopropyl alcohol for just 35 euro's. Now I'll just have to wait one week or maybe 2 weeks before I can harvest my plant and then get my ass in gear and work on some oil!

My little first plants!

Your first harvest. It may be closer to two weeks, maybe three.

 

[rikvasen]

Your first harvest. It may be closer to two weeks, maybe three.

Well it's still very soon thoug!! And I'm pretty happy and excited.

My little first plants!

 

[KingstonRabbi]

Your first harvest. It may be closer to two weeks, maybe three.

The cruelest words to hear on my first grow were 'wait' and 'patience.' It's like having a kid (or 4) in the back seat repeating, "Are we there yet? Are we there, yet? How about now?"

But be patient, Rik. The longer you wait the better oil your buds will make.

 

[rikvasen]

The cruelest words to hear on my first grow were 'wait' and 'patience.' It's like having a kid (or 4) in the back seat repeating, "Are we there yet? Are we there, yet? How about now?"

But be patient, Rik. The longer you wait the better oil your buds will make.

Well I don't find those words that cruel! I'm a patient person and I'm not bothered by waiting. I'm already happy enough that I came this far with so little resources I had. Next week I'll stop feeding her and maybe also next week I'll give her a good flush.

My little first plants!

 

[SweetSue]

A repost from my grow journal. Thought I'd already left it.

Green Flower Media (that's not a link) is offering a live-streaming class on "Cannabis Plant Chemistry" next Tuesday, Feb 28 at 5 PM Pacific time/ 8 PM Eastern. It's being taught by Arno Hazekamp, Head of Research/Education at Bedrocan, the Official cannabis program of the Netherlands.

I plan to be watching. I have a subscription that allows me access at any time starting the following morning, but I find Arno incredibly insightful and knowledgable about cannabis, and I want to experience him in real time.

Here's their explaination of the class and why they thought it important enough to share.

So many people work with cannabis but almost nobody really knows what’s actually in the plant or how it works on a molecular level. That can be a real problem when using cannabis as medicine, making cannabis products or cannabis extractions, and creating the right labels or regulations because people are making incorrect decisions without having a proper understanding of the plant.

In this new thorough Masterclass from one of the world’s top cannabis researchers, Arno Hazekamp will walk you step-by-step through the chemistry and biology of the cannabis plant, how the cannabinoids work, and why the plant science is so crucial for making informed cannabis decisions.

YOU’LL BENEFIT BY UNDERSTANDING:

How cannabinoids, terpenes, and flavonoids are actually made in cannabis

What is the chemical influence of extraction, degradation and evaporation on cannabis

The other ingredients found in cannabis that influence production and synthesis

What are realistic claims to make on cannabis product labels

The chemical differences between Sativa and Indica varieties

What you need to look for in cannabis lab tests

The chemistry of concentrated cannabis oils

Much more!

THIS MASTERCLASS IS FOR:

Growers looking to grow better cannabis

Product creators in the cannabis industry looking to create higher quality products

Medical professionals who want to truly understand why cannabis is medicine

Policy makers who are looking to make scientifically sound decisions

Patients who want to understand what’s truly in their medicine

This is a rare opportunity to learn the chemistry of the cannabis plant from one of the world’s leading cannabis researchers.

I agree with that closing statement. Arno is in his own class. I'm thrilled to have another opportunity to fine tune my knowledge base with his expert guidance. Join me. Share in this particular flavor of joyful expression. Knowledge is power. The more we know the less they can deceive us moving forward, and the more effectively we can support healing.

On top of that, Arno's fun to listen to. Very self-assured and confident. He can feel the excitement of what still lies ahead, and he's good at sharing the excitement.

 

[elronx]

would very much appreciate if someone could answare my question
short version- can you give cannabis oil to a leukemia cancer patient whilst hospitalized on chemo?
my gf was diagnosed with leukemia. she is currently hospitalized during chemo for 2 weeks and we are yet to aquire medical weed, now i got her a high quality cannabis oil of two bottles, one is 10thc/2cbd and the other 15cbd/4 thc now we asked a website that supplied similar bottles if its good being give to a leukemia patient and they said its not advised, the doctor at the hospitable said we are waiting for bureaucratic crap till we get it so basically if we had it now we could give it to her

 

[rikvasen]

So I just got my new vaporizer: White Rhino Dübe 2. But the liquid tank doesn't work. I think because the liquid tank doesn't connect to the battery properly. Can anyone help me further out?

My little first plants!

 

[kelticBlue]

Can anyone help me further out?

Wish I could but i will give the post a bump

 

[Canyon]

Good morning Sue,

I have been short on time for posting for a while.

I joined the GF site. I will probably pay the 18 dollars if I am around on Feb 28.

With the strain count I have and a few I have on order, (They have been in LA for 15 days now.) it covers a lot of things I am trying to understand better.

Any idea how much time to block out for the presentation.?

Best

 

[KingstonRabbi]

I signed up for GF masterclass but not sure I'll be able to get off work in time to watch live. (month end, joy) I may have to join to see it. I should do it anyway. Time to up my canna-education. Thanks for posting about these classes.

 

[KingstonRabbi]

Speaking of GF, do they have course on why effects persist after steady use? Or does anyone have info on it?

I'm having a lot more breakthrough euphoria than usual today and I haven't had a dose since 8pm last night (17 hours ago). I'm actually feeling more high right now than when I took the dose last night. To clarify, I take suppositories so I don't usually feel high. Last night as with most doses I didn't feel high but could feel the tinglies through my body and a gentle mood lift. Right now I would say I'm moderately high and was high most of the morning, too high to be at work. I've felt this before and thought it was breakthough from the doses I took during day, which led me to stop daytime doses after my last scan.

It's strong enough high that I feel like I should do a smoke report on it! <--and this is what I'd look like after I did.

I have all sorts of ideas but can't find anything to confirm any of them, so really no idea.

 

[Anchutz]

No, not necessarily. I am not sure exactly what it is in marijuana that effects the blood pressure and heart rate. Not so sure it is THC or CBD. There are over 80 known canibinoids and it is not only THC that is a psychoactive component.

The more pure the THC, the more comfortable the buzz is for me, less chances of a panic attack.

Strain can play a part as well. I wouldn't focus on the THC, high CBD is overrated anyway in my opinion.

Just curious, had she ever smoked or used marijuana before? New experiences can cause panic. Even if she has smoked, how about eating? That is different.

Has anyone heard about sucking on peppercorns to stop the panic attacks? Is this bad mojo?

 

[KingstonRabbi]

Has anyone heard about sucking on peppercorns to stop the panic attacks? Is this bad mojo?

It works. Caryophyllene in the peppercorns is anti-anxiolitic.

 

[SweetSue]

Speaking of GF, do they have course on why effects persist after steady use? Or does anyone have info on it?

I'm having a lot more breakthrough euphoria than usual today and I haven't had a dose since 8pm last night (17 hours ago). I'm actually feeling more high right now than when I took the dose last night. To clarify, I take suppositories so I don't usually feel high. Last night as with most doses I didn't feel high but could feel the tinglies through my body and a gentle mood lift. Right now I would say I'm moderately high and was high most of the morning, too high to be at work. I've felt this before and thought it was breakthough from the doses I took during day, which led me to stop daytime doses after my last scan.

It's strong enough high that I feel like I should do a smoke report on it! <--and this is what I'd look like after I did.

I have all sorts of ideas but can't find anything to confirm any of them, so really no idea.

I encourage you to subscribe with them. The classes are getting better. I don't recall anything about the lingering effects. There is a class I want to give you advance notice of, because when it opens up it fills quickly. They offer a master class on dosing and administration for specific treatments, taught by a couple physicians that work with the site. It costs $50, and I missed out when it ran the first time. I've been waiting on it for a while, trying to remember to set the money aside. It comes with the benefit of being able to ask the doctors directly and getting a personalized answer. This would be the place to ask that question KR.

 

[HashGirl]

I wonder if pinene is the reason why it was reported in the news that long term users of cannabis sometimes develop a syndrome that causes intense nausea and vomiting???

Why can’t some stoners stop puking? | Fusion

Or the info in the media could just be fear mongering.

From an industrial safety sheet on pinene.


Health Hazard
Harmful if swallowed, inhaled or absorbed through skin. High concentrations are extremely destructive to mucous membrane and upper respiratory tract, eyes and skin. Symptoms of exposure may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. (USCG, 1999)

 

[KingstonRabbi]

I wonder if pinene is the reason why it was reported in the news that long term users of cannabis sometimes develop a syndrome that causes intense nausea and vomiting???

Why can’t some stoners stop puking? | Fusion

Or the info in the media could just be fear mongering.

I doubt pinene is involved in cannabinoid hyperemesis syndrome. CHS occurs after long term use, and is rare but real. The symptoms listed for pinene are immediate. It's unclear exactly why CHS occurs, but most likely explanation is change in way Central Nervous System and Parasympathetic NS react to THC with prolonged regular use. Effect on PNS causing vomiting starts to outweigh antiemetic effect on CNS.

 

[SweetSue]

Sous Vide Without Plastic

Found this in my inbox this morning. The thing that stopped me from trying sous vide was the set-up expense and plastic. Not a fan of mixing my trichomes and plastic. This may be my ticket in. I had to share the joy with all of you.

 

[Jacobsenji]

SS
I watch a show called Bong Appetit and saw this once on there, just a short clip of them doing it. I remember at the time thinking damn too bad they used plastic to do that. Ruined it for me.
I went to the link you posted and want to thank you for that.
Have an amazing day

 

[Danolo]

Dosage limits..

I'm still a little confused about the dosage of these bio bombs for my wife's RA.

Right now she has been taking 4 bio bombs a day, each one having an equally balanced level of THC and CBD, at 22.6 mg for each bio bomb, or about 90 mg of cannabinoids per day.

Is this enough? Too much?

She has been experiencing some marked improvement in her symptoms, but still on high-humidity days she suffers a lot.

Sue, I read what you wrote about tolerance levels:

The only reason to increase would be if she's getting regular breakthrough pain that suggests a need for more THC. If you simply increase without good reason you run the risk of overshooting the optimal therapeutic dose and find yourself with the options of resetting the tolerance levels or increasing the dose to levels that aren't easily sustainable.

So, how do we know when she's reached the optimal tolerance level? Is there any guideline as to how much is the right amount?

I AM running into cost issues, so I do not want to waste the CCO I buy, and I want to make sure she gets everything she needs. I'm not willing to scrimp on what is necessary, and I'm not willing to waste it.

I'm just at the point where I have to make some more bio bombs for her and I'd like to know should I increase the cannabinoids or decrease?


I'd be glad of some further guidance...

Thanks, Sue