SweetSue's Cannabis Oil Study Hall

[ginganinja30]

While I was looking up info on Hashgirl's question about pinene I came across some background info that led me to this research article on reintoxication that answers my question above on why I was getting high more than 12 hours after my last dose the night before that didn't get me high.

Reintoxication: the release of fat-stored Δ9-tetrahydrocannabinol (THC) into blood is enhanced by food deprivation or ACTH exposure

It turns out that some THC is stored in fat tissues as THC and gradually released back into the body. This is usually a slow process but can be accelerated by certain chemicals through lipolysis and also by exercise and food deprivation that cause body to start metabolizing fat stores. In my case the large doses I took Thursday night were much closer together than usual, kind of a super-dose that apparently caused much more THC to be stored and then released in large doses throughout day Friday while I wasn't taking my supplements for competetive inhibition and therefore got me high all day long.

What I had read before was that only non-psychoactive metabolites were stored for long periods. This article and its references all confirm that THC and psychoactive metabolites are also stored and released over time.

The implications of this are widespread. It explains a lot of other things I've been experiencing during my treatment. It also partly answers many questions i've been researching since I joined this site, longer actually. It brings me to a point where I'm ready to start my biochemistry study hall to zero in on how cannabinoids travel through body to reach their target. I've got my note cards and yellow pad out to work on the first entry. It will take me a while to get it organized to point that it makes sense to others, but with peer pressure behind me I will see it through to fruition.

I'm keeping an eye out for this Kingston ...


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[FeloniousPunk]

Hi All,

I have a friend on his first grow, but if my calculations are correct and the grow goes full term without forced flowering, this crop will be properly dried and cured around the end of June. I know he needs these meds for pain relief and am worried he will jump the gun and not follow through with proper techniques.

My question is this:

Can you make quality oils or tinctures with a green (not dried and cured) crop. I know the drying and curing phases are very important to smokables, but do these benefits carry over to oils, etc? I know we have to decarb it no matter what, but will a fast dry in the oven spoil it? Can you take part of the crop, dry/decarb in the oven and make a decent medicine with it, or do you just have to be patient with it?

 

[Anchutz]

No, so I ran to sprouts and bought some sunflower lecithin. Weird flavor and consistency. How much lecithin do you use? What setting do you use on your MB2? Also heard the if you wash your weed with water it reduces the chlorophyll and makes edibles taste better, but don't want to lose potency. Thoughts?
Thank you,

 

[Anchutz]

Switching off strains will work to keep tolerances at bay. There are circumstances like your own that keep one from going off meds for any time.

With the MB2 you're gonna end up with a mess no matter what. I've found that processing two cups of oil is the minimum amount that works well for me. My standard measure is 100 grams of dried bud to 500 ml of oil. That's fairly potent. Are you using liquid sunflower lecithin to increase bioavailibity?

Thank you for your insights. Potency seems to be the key to reducing nerve pain and constant nausea from peripheral neuropathy. So, I ran to Sprouts and bought some sunflower lecithin. Weird flavor and consistency. How much lecithin do you use? What setting do you use on your MB2? Also heard the if you wash your weed with water and dry it reduces the chlorophyll and makes edibles taste better, but don't want to lose potency. Thoughts?

Thank you,

 

[Anchutz]

Switching off strains will work to keep tolerances at bay. There are circumstances like your own that keep one from going off meds for any time.

With the MB2 you're gonna end up with a mess no matter what. I've found that processing two cups of oil is the minimum amount that works well for me. My standard measure is 100 grams of dried bud to 500 ml of oil. That's fairly potent. Are you using liquid sunflower lecithin to increase bioavailibity?

Curious as to means of reducing $ when growing is not an option. Advanced stages of peripheral neuropathy causes a pain and pressure that high doses of opiates don't seem to help much. It's tolerance I'm sure. OTC pain meds are really bad for you. Anyone with a regimen that accommodates those type of considerations with cannabis?

 

[Danolo]

Like you, Anschutz, I find it difficult to grow. So, I have to rely on CCO produced by others. For now, I buy from a local dispensary.

On the issue of lecithin, I think it is suggested that we use liquid lecithin. Scroll back and you;ll find Sue's words of wisdom on this matter.

 

[Danolo]

Curious as to means of reducing $ when growing is not an option. Advanced stages of peripheral neuropathy causes a pain and pressure that high doses of opiates don't seem to help much. It's tolerance I'm sure. OTC pain meds are really bad for you. Anyone with a regimen that accommodates those type of considerations with cannabis?

I too am running into cash problems, with buying my CCO at a dispensary, right now at current dosage levels I'm going into deeper debt by about $300 a month. My only solution is to grow, or find a cheaper place to live. So, I'm looking for a place. But we are very settled here, in a safe, clean environment, so moving is going to be hard.

But despite that we will continue on with her treatment using Bio Bombs. We are now about three - 4 weeks along and she's experiencing some real improvement, in both pain relief and reduced inflammation. The improvement we've seen using this CCO in BioBombs is worth every penny.

Thanks Sue

 

[SweetSue]

Hi All,

I have a friend on his first grow, but if my calculations are correct and the grow goes full term without forced flowering, this crop will be properly dried and cured around the end of June. I know he needs these meds for pain relief and am worried he will jump the gun and not follow through with proper techniques.

My question is this:

Can you make quality oils or tinctures with a green (not dried and cured) crop. I know the drying and curing phases are very important to smokables, but do these benefits carry over to oils, etc? I know we have to decarb it no matter what, but will a fast dry in the oven spoil it? Can you take part of the crop, dry/decarb in the oven and make a decent medicine with it, or do you just have to be patient with it?

PsyCro has a fresh-harvest infused oil method that he claims is extremely potent. Hers a link to the blog on it. This linked post includes a link to his thread too.

PsyCro's Olive Oil Extraction Method

 

[SweetSue]

No, so I ran to sprouts and bought some sunflower lecithin. Weird flavor and consistency. How much lecithin do you use? What setting do you use on your MB2? Also heard the if you wash your weed with water it reduces the chlorophyll and makes edibles taste better, but don't want to lose potency. Thoughts?
Thank you,

Budwashing is recommended as a safety feature, as much as anything else, but it will enhance the drying and curing processes as well, and I believe it gives a smoother, cleaner inhallation, with no loss to potency. There are many tutorials on site to help you with this technique.

My standard for the lecithin is one tablespoon per cup of oil. The setting on the MB2 would depend on what you're using it for. I like to let Supergroomer cover MB2 questions, since his gets so much more use than mine.

Potency is needed for pain, but when you can balance the ratios of the major components they work much, much more effectively than with a high THC value alone.

As to cost reduction, this is why we push the BioBomb mentality so much. When you can take the bioavailability from around 12% to upwards of 90% you're getting much more bang for your buck. The cannabinoid load in the BioBomb capsules are potentiated by the carrier oil and the lecithin way beyond what others are dealing with.

We're so far out ahead of the curve here, it's almost frightening. This potentiating the meds isn't something I'm seeing anywhere in the mainstream MMJ community.

 

[SweetSue]

I too am running into cash problems, with buying my CCO at a dispensary, right now at current dosage levels I'm going into deeper debt by about $300 a month. My only solution is to grow, or find a cheaper place to live. So, I'm looking for a place. But we are very settled here, in a safe, clean environment, so moving is going to be hard.

But despite that we will continue on with her treatment using Bio Bombs. We are now about three - 4 weeks along and she's experiencing some real improvement, in both pain relief and reduced inflammation. The improvement we've seen using this CCO in BioBombs is worth every penny.

Thanks Sue

Oh Danolo..... You made me tear up with joy. Give her a big hug for me.

 

[New B]

I have a question that has probably been answered already. Why do we need to make CCO and then add to oil? Why does infused oils not do the same?
Is it so the oil it taken through the liver and CCO is not?

First Grow For Me - So First Journal Also

 

[SweetSue]

I have a question that has probably been answered already. Why do we need to make CCO and then add to oil? Why does infused oils not do the same?
Is it so the oil it taken through the liver and CCO is not?

First Grow For Me - So First Journal Also

Infused oils are just another way to administer. CCO allows you to get a much higher concentration of cannabinoids into the system, simply because they're so concentrated in the oil. That concentration won't happen in an infused oil.

Done properly, when you purge the ethanol from the washes you're left with almost pure oil, harvested from the trichomes. We add the carrier oil back in because the bonding of the cannabinoids to the carrier oil assists more rapid absorbtion into the system.

You avoid the first pass of the liver by choosing a long-chained fatty acid, like olive oil, which will be absorbed before hitting the liver. Unless you're treating liver cancer, we recommend olive oil.

 

[Anchutz]

Budwashing is recommended as a safety feature, as much as anything else, but it will enhance the drying and curing processes as well, and I believe it gives a smoother, cleaner inhallation, with no loss to potency. There are many tutorials on site to help you with this technique.

Hello Sue,

Thanks so much for the info. What about washing buds, say from a dispensary, to remove any surface contaminates, fertilizers or such or is that a non-issue. I heard of some washing to remove some of the weed taste, could it or should it be done?

Just for clarification (I'm not stoned so it must be age) major components being the terps? Are "balances" different for everyone and it's an adventure finding your own best balance or does everyone look for 1:1 ratio CBD to THC? I'm concerned I am approaching this the wrong way? I had some 30% Indica and it seemed to work better than a higher CBD strain but I was feeling it quite a bit.

Thanks a bunch for letting me pick your brain. I haven't seen much elsewhere on bioavailability either, I'm sure there are pot chemists working on it. The possibilities for some time spent trying it is sure worth it. If we make it too inexpensive and lower cost with your body using it more efficiently? Pretty slick! What would big pharma do? Diet is just one way of doing it, but it sure makes sense. The rest is just pissed away as they say.

Thank you

 

[JuanCarlos]

Hey Sue, sending you a PM now.

 

[rikvasen]

I bought some nice little things that could come in handy for myself in the upcoming time.

My little first plants!

 

[VerdantSpires]

I use dried mango weekly and green tea daily. Mango also helps THC cross blood-brain barrier, so you may feel effects more strongly. Up to you whether that's a good thing or not.

Is there a reason to restrict the mango to one day per week, or is there any benefit in eating mango each day?

Is there any option to specifically mango? It isn't like mangoes are available all year around, though in times of abundance a substantial quantity could be frozen if unrivalled in its value to ones cannabis treatment.

 

[SweetSue]

Budwashing is recommended as a safety feature, as much as anything else, but it will enhance the drying and curing processes as well, and I believe it gives a smoother, cleaner inhallation, with no loss to potency. There are many tutorials on site to help you with this technique.

Hello Sue,

Thanks so much for the info. What about washing buds, say from a dispensary, to remove any surface contaminates, fertilizers or such or is that a non-issue. I heard of some washing to remove some of the weed taste, could it or should it be done?

Just for clarification (I'm not stoned so it must be age) major components being the terps? Are "balances" different for everyone and it's an adventure finding your own best balance or does everyone look for 1:1 ratio CBD to THC? I'm concerned I am approaching this the wrong way? I had some 30% Indica and it seemed to work better than a higher CBD strain but I was feeling it quite a bit.

Thanks a bunch for letting me pick your brain. I haven't seen much elsewhere on bioavailability either, I'm sure there are pot chemists working on it. The possibilities for some time spent trying it is sure worth it. If we make it too inexpensive and lower cost with your body using it more efficiently? Pretty slick! What would big pharma do? Diet is just one way of doing it, but it sure makes sense. The rest is just pissed away as they say.

Thank you

I do not believe budwashing the product you purchased would be beneficial, and might be extremely detrimental to the trichomes. We budwash at harvest, when the plant and the trichomes have lots of flexibility and the only trichomes damaged are ones already compromised.

The smell diminishes because most of that was volatile monoterpenes. You lose up to 50% of them while the plant hangs and drys anyway, so not the concern it might appear, unless your goal is to retain as many terpenes as possible, in which case you'd be processing it into oil right then and there. I hear the new wave of oil producers are doing this by freezing the plant material within four hours of harvest.

Now, teach me how they process it from that point and I'm gonna dance a jig around my kitchen.

Cannabis expresses individually with each patient, so yes, you start every regimine at a sub-therapeutic dose and follow the slow and methodical process of titration until you find that patient's optimal therapeutic dose. The ratios you'll end up with will be determined first by what we're treating, and then by the tolerance levels of the patient. What we're beginning to discover though is that a balanced ratio is an excellent beginning point, and will effectively treat a myriad of concerns, including chronic pain, a fact that surprised most of us. Conventional thought was high THC for pain. Turns out we we're wrong in most , but notably, not all cases. A good rule of thumb is start at a balance of THC and CBD and then you fine tune for the individual.

If you try it in one direction (i.e. High THC, low CBD) and it doesn't work, flip it. Weight has nothing to do with dose, in the sense that a 140 pound woman can require a much larger dose than a 300 pound man for the same disease, at the same stage.

We're all lab rats around these parts. Until our federal government grows a pair that is.

Cajun once described it to us as the cannabinoids being the engine of the vehicle and the terpenes the steering system. The cannabinoids have the heavy-hitting potential, but it's the synergistic dance between cannabinoids and terpenes that get everyone in step and potentiates the medicine.

CBD works in ways no one really understands, at this point. There's speculation it's been misnamed as a cannabinoid, since it appears to have the ability to multitask. But you might not feel its effects until you stop taking it. I can testify to that. I ran short on CBD-dominant capsules before my next harvest, and took myself off my regimine to have enough on hand for my daughter. Her needs supersede my own. This has been going on for about a month now, and I'm beginning to see a resurgence of the patches of psoriasis that had begun to clear while I was on a regular schedule of dosing.

I'm working on training my ECS to heal without outside input. After all, we were designed to heal. Lab rat #1 here.

CBD both extends the euphoric effects of THC and tamps down extreme euphoric expression, simultaneously. That's only one example of the amazing capabilities of CBD. But on its own it's nowhere near that useful. Same with THC. Pair them together and you have a cannabinoid power couple. It thrills me to consider how much more learning we have ahead of us as we get into the "minor" cannabinoids and discover there was nothing minor about their effects on the human body.

You balance the ratios by individual patient. There is no standard dose in cannabinoid therapy, only starting points. Cannabis makes you pay attention, but won't smack you with ugly side effects when you overshoot. All you need do is back off until you're comfortable and then proceed with letting the natural healing commence.

Hey...... I don't know about you, but I've been growing younger for the past three years. Not really working that hard at it either. You should spend more time around me, it might rub off on you and you'll never say that crazy thing about your sparklingly intelligent brain and it's marvelous capabilities of recall and communication.

Sorry, I'm an extreme morning person, and you stepped right in front of me when I was feeling particularly loving. That usually sweeps everyone in the room closer to me or drives them running for the hills. Good morning. You got a pretty big dose of SweetSue there. That deserves a hug.

Hey Sue, sending you a PM now.

Got it. You have my back, I have yours my friend. I expect you to post pictures.

I bought some nice little things that could come in handy for myself in the upcoming time.

My little first plants!

Well, you're planning to jump right into the adventure, don't you. Correct me if I'm wrong, but you don't use cannabis at all, do you? Hmmmm..... I warn you, this bug you caught about medicinal cannabis is a difficult one to walk away from. Once bitten few of us get our lives back to where they were before - not that a single one of us would choose to be anywhere different, just that I don't think a single one of us considered at the outset how much this would change our lives.

I admire your interest and growing passion. Just wanted you to know that.

 

[rikvasen]

I do not believe budwashing the product you purchased would be beneficial, and might be extremely detrimental to the trichomes. We budwash at harvest, when the plant and the trichomes have lots of flexibility and the only trichomes damaged are ones already compromised.

The smell diminishes because most of that was volatile monoterpenes. You lose up to 50% of them while the plant hangs and drys anyway, so not the concern it might appear, unless your goal is to retain as many terpenes as possible, in which case you'd be processing it into oil right then and there. I hear the new wave of oil producers are doing this by freezing the plant material within four hours of harvest.

Now, teach me how they process it from that point and I'm gonna dance a jig around my kitchen.

Cannabis expresses individually with each patient, so yes, you start every regimine at a sub-therapeutic dose and follow the slow and methodical process of titration until you find that patient's optimal therapeutic dose. The ratios you'll end up with will be determined first by what we're treating, and then by the tolerance levels of the patient. What we're beginning to discover though is that a balanced ratio is an excellent beginning point, and will effectively treat a myriad of concerns, including chronic pain, a fact that surprised most of us. Conventional thought was high THC for pain. Turns out we we're wrong in most , but notably, not all cases. A good rule of thumb is start at a balance of THC and CBD and then you fine tune for the individual.

If you try it in one direction (i.e. High THC, low CBD) and it doesn't work, flip it. Weight has nothing to do with dose, in the sense that a 140 pound woman can require a much larger dose than a 300 pound man for the same disease, at the same stage.

We're all lab rats around these parts. Until our federal government grows a pair that is.

Cajun once described it to us as the cannabinoids being the engine of the vehicle and the terpenes the steering system. The cannabinoids have the heavy-hitting potential, but it's the synergistic dance between cannabinoids and terpenes that get everyone in step and potentiates the medicine.

CBD works in ways no one really understands, at this point. There's speculation it's been misnamed as a cannabinoid, since it appears to have the ability to multitask. But you might not feel its effects until you stop taking it. I can testify to that. I ran short on CBD-dominant capsules before my next harvest, and took myself off my regimine to have enough on hand for my daughter. Her needs supersede my own. This has been going on for about a month now, and I'm beginning to see a resurgence of the patches of psoriasis that had begun to clear while I was on a regular schedule of dosing.

I'm working on training my ECS to heal without outside input. After all, we were designed to heal. Lab rat #1 here.

CBD both extends the euphoric effects of THC and tamps down extreme euphoric expression, simultaneously. That's only one example of the amazing capabilities of CBD. But on its own it's nowhere near that useful. Same with THC. Pair them together and you have a cannabinoid power couple. It thrills me to consider how much more learning we have ahead of us as we get into the "minor" cannabinoids and discover there was nothing minor about their effects on the human body.

You balance the ratios by individual patient. There is no standard dose in cannabinoid therapy, only starting points. Cannabis makes you pay attention, but won't smack you with ugly side effects when you overshoot. All you need do is back off until you're comfortable and then proceed with letting the natural healing commence.

Hey...... I don't know about you, but I've been growing younger for the past three years. Not really working that hard at it either. You should spend more time around me, it might rub off on you and you'll never say that crazy thing about your sparklingly intelligent brain and it's marvelous capabilities of recall and communication.

Sorry, I'm an extreme morning person, and you stepped right in front of me when I was feeling particularly loving. That usually sweeps everyone in the room closer to me or drives them running for the hills. Good morning. You got a pretty big dose of SweetSue there. That deserves a hug.





Got it. You have my back, I have yours my friend. I expect you to post pictures.



Well, you're planning to jump right into the adventure, don't you. Correct me if I'm wrong, but you don't use cannabis at all, do you? Hmmmm..... I warn you, this bug you caught about medicinal cannabis is a difficult one to walk away from. Once bitten few of us get our lives back to where they were before - not that a single one of us would choose to be anywhere different, just that I don't think a single one of us considered at the outset how much this would change our lives.

I admire your interest and growing passion. Just wanted you to know that.

Well I never used it but I have some problems where those products can come in handy. I will send you a PM when you are interested and curious about why. But I'm a little busy now so I will talk to you later on this day.

My little first plants!

 

[Dave Groomer]

Ok guys and gals. I have a friend who was just diagnosed with a large fibroid uterine tumor. The problem is that she also is suffering from a blood disorder that is throwing clots so she is not a candidate for surgery. Anyone treated fibroids with CCO?

 

[KingstonRabbi]

Is there a reason to restrict the mango to one day per week, or is there any benefit in eating mango each day?

Is there any option to specifically mango? It isn't like mangoes are available all year around, though in times of abundance a substantial quantity could be frozen if unrivalled in its value to ones cannabis treatment.

I use dried mango and tend to binge feed on them when I have them, so I only get them once a week. No harm in having it daily. Juice is good also as long as it's actually from mangos and not just mango flavored made from other fruits. Hopefully Sue will chime in with list of other foods that will work.