Here is my reply to your latest note.
The only reason I wouldn't consider the suppositories now is that I'd have to make them and I'm not sure I could. I'd be very happy not to have the high.
Making the oil with MB2: The MB2 comes with a straining bag. There are a couple of videos about it on you tube. After you strain it through the bag you leave it to air evaporate overnight in a shallow dish with a small fan running. Then you scrape the oil together.
Do any of the prescriptions come with a warning to avoid grapefruit juice? -No
You made the suggestion that I begin juicing daily; but I'm hesitant to ingest the raw cannabis because of my problems with the oil. If the problem is due to the chlorophyll, won't I get sick?
I have a cannabis card (massachusetts). I can buy plant material, oil, kief, rosin, etc. In fact I have 2g of rosin in my freezer. I decarboxylated rosin and haven't had any reaction to it but have not increased the dose much because I couldn't figure out how to make it into a large enough dose. As far as I know though I don't react to it like I did the RSO. I guess we'd have to see.
I'm interested in these biobombs. Are these suppositories? If not, what exactly are they?
And I have 100 pounds to lose.
Gnite for now.
Eventually your ECS will become balanced enough that your appetite will change and those excess pounds will fall away. You don't want to lose them, because then the brain starts looking for ways to find them, and it always manages to do that with a couple more pounds added on.
It's one of those subtle language things tied to emotion that I was speaking about. At least I think it was in this room I was having that discussion. You want to let those pounds go, pure and simple. Appetite control and digestion are both regulated by ECS signalling.
Capsules make excellent suppositories. Much easier than molds, and more easily transported for dosing away from home. If you have rosin available I'd go for the biobombs and use them as suppositories. I agree, if the chlorophyll is the problem then juicing isn't your answer. However, after you've been using biobombs for a few months I'd give it another try. Chlorophyll is a valuable nutrient, and as your ECS becomes more efficient you'll find that things don't have the same effect on you.
As you'll see with the biobombs, dose effectiveness has to do with more than just cannabinoid count. Finding your personal dose with suppositories is different than when you dose through the gut. You already have a tolerance for THC, so I'd go straight to the 5:1 formulation, do 3-4 doses a day and stay there until you have some labs to review the efficacy of the dose. Start with two doses and add in one more dose every four days. If you feel out of sorts at all, slow it down by backing off one dose. Keeping doses uniformly-spaced keeps constant cannabinoid presence in the system.
Are you taking any steps for competitive inhibition? The liver enzymes that metabolize cannabinoids also metabolize a couple other compounds, so if you take two apignen capsules 30-45 minutes before a dose of cannabis oil you can overwhelm the enzyme action and potentially squeek more cannabinoids through without being metabolized. Eating mangos at the same time will help the body clear methyl groups from the receptors, opening up more opportunities for cannabinoid signalling. The first couple pages of
CajunCelt's cancer regimen thread is rich in information on increasing bioavailability.
We don't recommend you make a concentrated oil in the MB2, despite their instructions. It's too easy to burn the oil, and it'd be crazy difficult to clean the machine afterwards, I'd think. Not only that, but I'm certain you'd end up with lots of chlorophyll in the resulting concentrate. A quick-wash method is the way to go for CCO. The MB2 shines as a way to make infused oils and tinctures, but we have much better ways to make a quality CCO.
Making an infused oil with dried and cured buds eliminates the concern over chlorophyll. Biobombs made from purchased concentrate will give you the biggest bang for your buck and be the easiest for your brain to manage, IMO.