SweetSue's Cannabis Oil Study Hall

SweetSue said:
Have you tried them orally? The dose is low enough she may tolerate it and it can be a nicer effect through the gut if you can get dosing down.

The benefit to two a day is to keep a more consistent level of cannabinoids in the system. However, there are many clinical reports of effective dosing once a day, so it's certainly worth a try.
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I'm reluctant to have her swallow them, because of the bioavailability as it passes through her digestive system.
How much is lost to digestive juices, liver, etc?

We WILL try one a day, shoved, once we get this recent batch encapsulated.

So, at 2 per day, she was getting a level of cannabinoids, to reduce the dosing to one a day, should we increase the concentration?
I'm reluctant to make them stronger and have her revert to falling asleep for 2 hours after shoving. Yet only taking one 15:1 will reduce the dosage of cannabinoids.

Whatcha think?
 
Danolo said:
I'm reluctant to have her swallow them, because of the bioavailability as it passes through her digestive system.
How much is lost to digestive juices, liver, etc?

We WILL try one a day, shoved, once we get this recent batch encapsulated.

So, at 2 per day, she was getting a level of cannabinoids, to reduce the dosing to one a day, should we increase the concentration?
I'm reluctant to make them stronger and have her revert to falling asleep for 2 hours after shoving. Yet only taking one 15:1 will reduce the dosage of cannabinoids.

Whatcha think?
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You won't know how they'll effect her orally until you try. She can't be hurt by trying oral, in that she won't lose any progress, and you might find that two capsules a day, spaced out equally, will be enough to keep her in balance.

To our understanding, cannabinoids don't hang around in the bloodstream very long. Best guess is 4-6 hours. They get absorbed into the fat cells, and the supposition is that they can be reintroduced into the system. We simply don't have the research to know what's really going on.

I'd try two capsules a day and see what happens Danolo. If you're going to stay with suppositories you might want to make that one a day 20:1 and see how that works. It's all trial and error, and you've been wonderful at that. :battingeyelashes: :Love:
 
Danolo said:
Well, I screwed that up... After giving my mixed oil 2 X 24 hrs in the fridge I set up to fill the capsules.

When I went to put the tops on, many of them broke and I spread oil all over the place!

I think my mixture might have been too warm and it melted the caps.

I have recovered much of the oil and I'm gonna try to encapsulate what's left... we'll see.
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Huh! I messed up! I tried filling another batch of caps and again, many of them did not seal, and some of them just melted in the capsule device.

Maybe, my impatience, led me to try filling the caps too soon and there was some water/moisture in the device that softened the caps. Or maybe this mixture is somewhat acetic and is melting these caps.

I dunno...

I hate to waste oil and dispose of the mixture to start over, but in a mix that should produce 30+ caps, I've made about 15 caps that I hope will be all right, and I suspect I've spilled enough oil to fill 2 -3 caps. There's still some mix left, and I'll wait until I am sure the device is dry and will try again this evening..

Meanwhile I cleaned up the spilled oil with a tortilla, and ate it, so I suspect my mood will improve a lot in the next hour or two. :)
 
AAAArgh...

I think the oil is melting the caps. I filled the rest of the mixture into caps, by hand, one by one, and they seemed to fill and close ok.
But now, 30 minutes later, many of them are leaking, or misshapen. When I gently touch a cap, it feels really soft.

So, either the mixture is softening the caps, or, the caps themselves have become thinner or more fragile.

My wife tried to shove one of these and it collapsed at some point in the process. I don't think it was a pleasant experience. :)

I've eaten about the equivalent of 2 -3 caps of oil, just cleaning up the spillage, so we'll see about how it affects me. If I come to no harm, then the oil is likely ok to use and if necessary, I'll squeeze it all out and make cookies, or something.
 
Danolo said:
AAAArgh...

I think the oil is melting the caps. I filled the rest of the mixture into caps, by hand, one by one, and they seemed to fill and close ok.
But now, 30 minutes later, many of them are leaking, or misshapen. When I gently touch a cap, it feels really soft.

So, either the mixture is softening the caps, or, the caps themselves have become thinner or more fragile.

My wife tried to shove one of these and it collapsed at some point in the process. I don't think it was a pleasant experience. :)

I've eaten about the equivalent of 2 -3 caps of oil, just cleaning up the spillage, so we'll see about how it affects me. If I come to no harm, then the oil is likely ok to use and if necessary, I'll squeeze it all out and make cookies, or something.
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Try freezing the capsules you have filled. They can be taken orally frozen. Worst case is you take them yourself.

Have you changed capsules? The only other thing that springs to mind is there might be solvent left in the oil. Is this a new batch of oil?

I can imagine she wasn't enchanted with the experience. :battingeyelashes:
 
SweetSue said:
Try freezing the capsules you have filled. They can be taken orally frozen. Worst case is you take them yourself.

Have you changed capsules? The only other thing that springs to mind is there might be solvent left in the oil. Is this a new batch of oil?

I can imagine she wasn't enchanted with the experience. :battingeyelashes:
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Freezing! That's good idea! we will try that...

As you may recall, the CCO I use I buy from a local dispensary. It has a fairly well known brand name andI have had no problems of this sort before.

Same batch of capsules..

Now in looking at these caps they are almost disintegrating. I'll try and attach a picture.

IMG_031557.JPG
IMG_031452.JPG


This is same capsules, one pic with flash, the other without.

Its kind of hard to see, but most of the caps are collapsed and leaking.
 
That is very strange...that was my only guess. Hope you figure it out,as I hate wasting oil.
Sorry for your luck. I'm sure it will turn around in a unexpected way.
 
New B said:
That is very strange...that was my only guess. Hope you figure it out,as I hate wasting oil.
Sorry for your luck. I'm sure it will turn around in a unexpected way.
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Yeah, thanks for your good wishes..

We'll try freezing them and see if she can swallow them. But I am also gonna go get a brownie mix... :)

And, I have to decide what to do about replacing them... I do need more Bio Bombs for my wife.

I might drop down to a local head shop and get some more (newer?) capsules..
 
Danolo said:
Sue, just check me on my recipe, please:

2 cc's of CCO
4 cc's of liquid lecithin
26 cc's of EVOO.

Is that right? I STILL get confused with the ratio for LL.

With 26 + 4 = 30 cc's to 2 cc's CCO

That's 15:1, right?

Thanks
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15:1 would be 1cc CCO, 12cc EEVO, 3cc liquid sunflower lecithin. That makes 16cc of mix.
 
Canyon said:
Danolo,
I suspect that you have some water in your oil. I had some problems with melting with a few caps of a batch of oil I made and water was defiantly the problem I had.

Luck
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It just about has to be that, or wrong capsule mtl or solvent in oil. They are decomposing right? not swelling and bursting?
 
Kicknitup1 said:
Hi all,
Does anyone have any tests that show what terpines survive decarb?
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Somewhere back in these pages is a post by neikodog that I haven't found yet that compared the lab testing of undecarbed bud with decarbed and processed oil. Most of the terpenes were destroyed in the process, even using the roasting bag. I'll ask him if he can share those, and any others he may have with us here.
 
Kicknitup1 said:
It just about has to be that, or wrong capsule mtl or solvent in oil. They are decomposing right? not swelling and bursting?
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The ones I had mostly had localized soft spots but I had small beads of water from trying to get the last bit of oil. That is why I am so sure my problem was water.

If your problem is water, it must be suspended in the oil. It sure looks like whatever is causing it is uniformly distributed.

I never lnow
 
Canyon said:
The ones I had mostly had localized soft spots but I had small beads of water from trying to get the last bit of oil. That is why I am so sure my problem was water.

If your problem is water, it must be suspended in the oil. It sure looks like whatever is causing it is uniformly distributed.

I never lnow
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If you warm up the oil first it seems like it would be hard for water to not separate....unless it is captured by the lsl.
 
Hmmm... water in the mix... I dunno HOW water got into it..

How much water can cause this problem? IF these was water, it would only be a few drops, I think. I mixed up a total of 32 cc's of mixture and there could not have been more than 1 cc of water... probably less.

What about the Lecithin? Is it hygroscopic? I have a large bottle and I transfer some into an eyedropper bottle every few batches, and when its time to use it I put the smaller bottle in a warm water bath to help it move. Maybe, MAYBE, some got dripped into the mix.

She just took one of the frozen caps, so we'll see what affect that may have. She took it orally... she wasn't enthusiastic about shoving a cold, messy, capsule.. :)
 
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