I was just talking to him today Sue I will drag us both back.
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We started out with the formula Cajun gave us, the one you were working from in your notes. Here in the Study Hall we determined a need to better control the dosages for higher cannabinoid loads, and this is what we came up with.
BioBomb Capsules - Continuing rework
20:1 = 1 cc CCO + 16 cc carrier oil + 4 cc lecithin
1000 mg cannabinoids /21 capsules = 47 mg cannabinoids per capsule.
10:1 = 1 cc CCO + 8 cc carrier oil + 2 cc lecithin
1000 mg /11 capsules = 91 mg cannabinoids per capsule
5:1 = 1 cc CCO + 4 cc carrier oil + 1 cc lecithin
1000 mg/6 capsules = 167 mg cannabinoids per capsule.
Sue and/or Canyon can you help me out here (again)?
I'm struggling with one aspect of these formulas. The cannabinoids per capsule seems to be based on 1000 mg of cannabinoids per cc/ml of CCO That would be what I was referring to earlier as Pure Cannabis Extract.
It reinforces my understanding that knowing the cannabinoid load in the capsules is very important perhaps essential.
My difficulty is in having no way to buy or make a CCO of that strength.
I'm wondering how to proceed..... any advice?
Some questions for colleagues:
2) Is there a standard recommended size of gel cap? I'm thinking size 000 might be best given ease of access to supply, plus you can put 1 ml liquid in there without it needing to be full which should be easier and less messy.
That sounds sensible, Bear... I may get 000's my next batch. The problem with it being less messy, is that I enjoy the cleanup!
3) i read on here somewhere that the depth of insertion of a rectal suppository makes a difference in how it is absorbed, and that changes the reaction in the body. If true it needs to be explained in the protocol. Is this correct: shallow gets absorbed directly into the blood stream and bypasses the liver. Deep gets absorbed in digestive track and goes through the liver. What about vaginal?
My wife suggests just dip the cap in a bit of hand lotion, or something slippery and just poke it in. Once past the sphincter, you are in the right place. Deeper than that you may be digesting it, rather than absorbing it. Then, clench... or lie down...
4) Is injection of the liquid using a syringe of some sort just as effective a treatment method?
Now THAT sounds messy!
5) We have all seen tampon commercials where the absorbing material is inserted by pushing it through a tube using a rigid pusher. Has anyone come across a similar tool for gel cap insertion?
Don't over think it, Bear, just shove it in!
Some questions for colleagues:
1) What is the generally accepted percentage of efficiency of extracting cannabis compounds from buds? Is 80% a good number? Does is change significantly based on the extraction method?
If true, that means that 20% is left over and I dont want to be throwing that out. Even if its 10% I want to use it - for baking or something.
According to Skunk Pharm the first wash of ethanol gets 75-80% and you'll get the rest with the next two washes. Making CCO with highest proof ethanol you can get almost 100% extraction. Infused oils have an extraction rate of around 85%.
2) Is there a standard recommended size of gel cap? I'm thinking size 000 might be best given ease of access to supply, plus you can put 1 ml liquid in there without it needing to be full which should be easier and less messy.
Most choose the 00 for dosing ease and don't worry about the little bit of leftover. Cannabis isn't a pharmaceutical and doesn't have have to be treated like one.
3) i read on here somewhere that the depth of insertion of a rectal suppository makes a difference in how it is absorbed, and that changes the reaction in the body. If true it needs to be explained in the protocol. Is this correct: shallow gets absorbed directly into the blood stream and bypasses the liver. Deep gets absorbed in digestive track and goes through the liver. What about vaginal?
Vaginal insertion is sometimes recommended. As a woman I wouldn't be happy about this one, but if I had uterine cancer you wouldn't get a peep of complaint out of me.
4) Is injection of the liquid using a syringe of some sort just as effective a treatment method?
Absolutely. We've had patients use this to great effect. It's a valuable option. Use 1ml syringes. I'm thinking of ordering some so I can test it out.
5) We have all seen tampon commercials where the absorbing material is inserted by pushing it through a tube using a rigid pusher. Has anyone come across a similar tool for gel cap insertion?
You are amazing Sue,while i dont even know you, i feel you have a spot in my heart. I am pretty sure I got it now, I have a 1-4-1 batch in the fridge right now. The 1-5-10 batch filled twenty caps. Should I use four at one time to get my daily dose ?Seems like a lot of caps to insert anally but the way I see it if I want that full gram dose I have to take all twenty in one day.Or...maybe I should just slip one extra dose in each day with the 1-4-1 caps till gone. Any thoughts ?
Update on the daughter's results
We've been having conversations about how she's handling the cannabinoid therapy and changes she's noticed. She shared that despite the capsules and the way they relieved her anxiety she still had lots of tension at night and would worry about falling out of bed. Any woman who fights for mattress real estate will appreciate her concern. We were giggling about how I'd wake up and her father'd left me a sliver of the bed. Anyway, she'd wake in the morning with sore muscles from the lactic acid overload. Moving was painful until she got things warmed up.
Well, recently she started having a bite of a Candy Cane brownie before slipping into bed and discovered she woke up completely relaxed and able to bound out of bed. Candy Cane is in the neighborhood of 15% THC I believe, and the brownies are equivalent to a half gram each with approx. 73 mg of THC apiece, so she's probably getting somewhere in the neighborhood of 15 - 20 mg in that little bite. She eats the rest of the brownie throughout the day. She's having a lot of fun doing things like having some brownie and going shopping. It's fun watching her explore life without the anxiety that's haunted her all this time.
And this plant is illegal why???????
That's great she enjoying herself
I think it's illegal for two reasons
One being: lots of wealthy
People like Pacific Northwest paper mill barons wouldn't be in the position there in and oil tycoons and of course pharma but just maybe it's also a form of population control
Some like the paper barons consider people like us "feeder fish" and want us to be gone
They knew what they were doing in 1937
I have a short term goal now
Make bio bombs!!
Good to hear. I have a different view of dosing than what I've been seeing out there in the medical community. My plan is to get you on a regular scheduled dosing of BioBombs and keep a constant pressure at lower doses rather than a couple larger doses or one singular dose a day. BioBombs are the best way I've found to do that.
I'm not really interested in symptom control, I'm focused on encouraging natural healing with a continuious load of cannabinoids. This is still in its infancy, but we're seeing promising results. And it's so easy once you have the oil on hand. You're really good at that part Hizzy.
Thanks a lot
Been busy all day trying to fix the car
Fun stuff