Depending on things such as the specific brand of nutrients you use and at what strength, some nutrient salt buildup can be... challenging to remove, IMHO. I might recommend that a person fill and "tilt to drain" their containers once in a while in order to discourage salt buildup. I'm guessing that, due to the drain hole being elevated and the relative stability of the setup (no constant circulation), that there isn't a great deal of flushing that takes place with just a little overflow during a regular feeding.
OtOH, the reservoirs are generally much smaller than, for example, a 23-gallon DWC. In theory, this is a downside - because there is less of a nutrient/water store for the plant to draw upon - but I'd guess that the plant in a small hempy might end up consuming most of its nutrients between waterings. Hmm... Flip a coin, lol? Again, brand of nutrients and nutrient strength would be important factors.
I've seen someone take short-flowering rooted clones, with no vegetative grow period while in the bottles, through to harvest without worrying about watering enough to produce significant overflow (actually, they seemed to attempt to avoid runoff, lol). IIRC, they used one of the commercial "flushing" additives at some time around the beginning of the last week of flower. This was a two-liter bottle grow. I was told the buds burned to a fine white ash - so no fertilizer buildup in them.
I probably won't be adjusting pH in mine ( :icon_roll ), so may end up trying to do simple water flushes from time to time. Maybe cover the hole with a piece of tape, fill the bottle, wait a few minutes, remove tape, tilt to dump reservoir, repeat? Hmm... I wonder if adding a surfactant (e.g., some kind of mild soap) would help during a flush - or if it would harm the root system and/or leave contaminants behind? Not something I'd try with something like Osmocote Plus in the containers (or on more than one plant at a time), but maybe on one that is receiving traditional hydroponic nutrients with the water. IDK.