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Hi bjax,Quote Originally Posted by bjax View Post
Thanks for your response. I realized after I submitted post that I posted to the wrong area. Sorry. To answer your questions. By the way the oil affected me when I was dosing orally, I'd say it's Indica and I should change to Sativa for daytime usage. I dose once in the am and once in the pm rectally. I'm still working my way up to the recommended dosage and by the fact I don't get stoned, I should be able to do this pretty quickly. When I was ingesting it, I didn't and don't believe I could ever reach the 1 gram/day dosage. Yes, I'm currently taking Creon as digestive enzymes, but my remaining pancreas is beginning to compensate for the Whipple procedure and I'm reducing my Creon intake. The cancer I had was a pancreatic neuroendocrine tumor. Think Steve Jobs. There was no evidence of disease at time of surgery, but now I have liver mets. I will try the tacking and hopefully that will work, but I want to ask, since the oil is being absorbed directly into the bloodstream and by-passing the liver initially, how does that affect the medicinal benefits of the oil on the liver lesions? Because these are liver mets and the liver is usually the first pass thru for things ingested, it may seem that I should be doing this differently in order to get the most benefit.?? I've tried to research the bioavailability of ingesting vs suppositories and there's so much conflicting information that my head begins to swim. Thanks.
There is a lot of conflicting information to be sure. Think you found a great site to get unconfused. If you wouldn't mind I'll C&P this and move it to the main dosing thread to keep things better organized. Also we are finding out that that gum absorption/tacking protocol and bioavailability of ingesting/suppositories can come together as a perfect marriage. I don't think many subscribe to this thread. Just briefly; as mentioned, getting the oil to your CB1 receptors first keeps the body regulated so there is no high regardless of what protocol you use. Not only no high but your body is regulated in many ways. cajuncelt is using this combined dosing regimen as we speak. His expertise on bioavailability digesting and suppositories and my wife and I studies on gum absorption/tacking protocols are coming together rapidly and we are both excited how our combined knowledge is all coming together to end a lot of confusion. Yes, it is already out there but the pieces of the puzzle has been vague to say the least. We have learned this mostly on our own as we continue to gain knowledge, share this information to end the confusion so people can heal themselves with confidence instead of confusion. I cannot speak for cajuncelt but the pieces of the puzzle to help others in my opinion are there. We have much more to learn exactly how what does what. For me personally the wife and I are learning the 'power' of the brain when its activated with cannabinoids in the CB1 receptors first. Ailments get fixed before the brain gets woken up as your brain gets its CPU repaired. So much knowledge comes pouring in it's flat out amazing. Enough on this right now. canjuncelt should pipe in when he see's this thread as mentioned he is using combined protocol exactly what your going through. I'm still on light duty getting things organized on the home front as well as some much needed R&R and a ton of other things.
Cheers
Motoco