For what it is worth, when my wife went through non-surgical recovery from multiple broken bones in her foot: In a state with Medical Marijuana, NONE of her doctors or nurses had an issue with combining cannabis with opiods, anti-coagulants, stool softeners, etc. They had her go off several of her herbal supplements when she was on the warfarin (for blood clots preventing her from having surgery) but they all encouraged her to continue using the cannabis at as high doses as needed to control her pre-existing medical conditions as well as to supplement the newly prescribed pain meds.
Then again, the medical professionals didn't know a whole lot about medical Marijuana and asked her questions about it's effectiveness for various conditions. It was a very long process, but her initial bone healing was faster and more complete than expected.
P.S. She was using typical high THC / low CBD strains developed for recreation (White Widow, AK47, Hawaiian Skunk, etc.)