Recess Is Over - Now To Muck Up The Lesson

:rofl: who? :rofl:
 
I need some links to good cannabis medical threads or articles.. I'm working at a doctors house and after a good conversation she wants to look into it more.. thanks in advance all..
 
GrizzWald said:
I need some links to good cannabis medical threads or articles.. I'm working at a doctors house and after a good conversation she wants to look into it more.. thanks in advance all..
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Like just a site saying what strains do what? Or you talking the biochemical level where with cannibinoids attack cancer

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Yeah, just some good deep info on the benefits and science of that.. I've given her the motoco threads, was hoping for some medical articles or the like.. thanks..
 
Little bit of stuff I found, not sure if its technical enough ;)

Cannabinoids may inhibit tumor growth by causing cell death, blocking cell growth, and blocking the development of blood vessels needed by tumors to grow. Laboratory and animal studies have shown that cannabinoids may be able to kill cancer cells while protecting normal cells.

Cannabinoids may protect against inflammation of the colon and may have potential in reducing the risk of colon cancer, and possibly in its treatment.

A laboratory study of delta -9-THC in hepatocellular carcinoma (liver cancer) cells showed it damaged or killed the cancer cells. The same study of delta-9-THC in models of liver cancer showed that it had anti-tumor effects. Delta-9-THC has been shown to cause these effects by acting on molecules that may also be found in non-small cell lung cancer cells and breast cancer cells.

A laboratory study of cannabidiol (CBD) in estrogen receptor positive and estrogen receptor negative breast cancer cells showed that it caused cancer cell death while having little effect on normal breast cells. Studies of metastatic breast cancer showed that cannabinoids may lessen the growth, number, and spread of tumors.

A laboratory study of cannabidiol in human glioma cells showed that when given along with chemotherapy, CBD may make chemotherapy more effective and increase cancer cell death without harming normal cells. Studies showed that CBD together with delta-9-THC may make chemotherapy such as temozolomide more effective.

These studies are considered by the NCI as preclinical. They were all done using animals. According to them, no clinical trials of cannabis use for the treatment of cancer in humans have been published.
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Crohn's disease, one of several inflammatory bowel diseases, achieved "complete remission" in nearly half the subjects of one study that were exposed to smoking medical marijuana on a regular basis.
Published in the journal Clinical Gastroenterology and Hepatology, the study-examined the effects of consistent marijuana use on Crohn's patients who suffered from severe cases of the disease. The results of the 21-subject study point toward the drug's anti-inflammatory properties as being responsible for quieting symptoms in many patients, and even reaching total remission in others.
The Disease: Causes, Symptoms, And Treatments
Often mischaracterized as an autoimmune disease, Crohn's disease is in fact an immune deficiency state. Arising from a host of genetic, environmental, and immunological factors, the disease causes a chronic inflammatory disorder that attacks the person's gastrointestinal tract — anywhere from the mouth to the anus — in order to fight the body's antigens that otherwise do no harm. Symptoms of the disease range from mild abdominal pain to more severe cases of bloody diarrhea, nausea, vomiting, weight loss, and fevers.
There is no cure for Crohn's; however, various methods are aimed at limiting flare ups and keeping the disease in remission. Treatments, like disease severity, fall on a spectrum depending on the person. Simple dietary changes suffice for some, while invasive surgery to remove the affected area may be needed for others. Corticosteroids and other medications are also prescribed for less severe cases.
The disease affects around 400,000 to 600,000 people in North America, although many people do not get diagnosed until they've had the disease for years, simply because no symptoms were present.
The Study And Its Findings
Scientists at Meir Medical Center in Israel wanted to examine the effects of Cannabis sativa-on patients with severe Crohn's disease, relying on the underlying drug's anti-inflammatory effects in treating other ailments, such as arthritis and multiple sclerosis.
"The marijuana plant Cannabis sativa-has been reported to produce beneficial effects for patients with inflammatory bowel diseases, but this has not been investigated in controlled trials," the researchers wrote. "We performed a prospective trial to determine whether cannabis can induce remission in patients with Crohn's disease."
Twenty-one people with severe, intractable Crohn's comprised the study. Out of those 21, 11 subjects smoked two joints a day for eight weeks. The other 10 made up the placebo group.
The results were particularly telling, according to the researchers. In total, five of the 11 subjects smoking marijuana daily achieved total remission of their Crohn's. They reported greater appetites and sleep patterns. (People with severe cases of Crohn's sometimes defecate 20 times per day, and may even wake up at night to do so.) Moreover, "a clinical response" was found in 10 of those 11. Only four of the 10 placebo subjects reported any improvements.
These findings, argued the researchers, demonstrate how "THC-rich cannabis produced significant clinical, steroid-free benefits to 11 patients with active Crohn's disease, compared with placebo, without side effects."
The researchers were hesitant to call the study a total success, however, saying that the "primary end point of the study (induction of remission) was not achieved," despite the five of 11 people who reported those effects.
Still, they noted that their findings merit further attention. "Further studies, with larger patient groups and a nonsmoking mode of intake, are warranted," they wrote, pointing to the potentially diminished effects of smoking marijuana, as opposed to extracting the anti-inflammatory drugs directly from the plant.
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So MNS is opensource while guys like GHS and DNA are the microsofts of this world? Ok, I can buy that. It's just frustrating how every breeder has their own version of the "truth". It makes it very hard to figure out who came up with what. As an example, Shanti vs Ingemar. The only thing I'm certain of, is that fans of Shanti's work will naturally defend him as the original creator of white widow. Thing is though, it's impossible to know for sure. So you go trawling the net for some decent examples of black widow, but then can't find any.

Also, if you aren't looking for breeding stock, what is the point? I don't want to drop 6 regs and come up empty handed.

The allure of black widow is strong though! So my next seed purchase will include 6 beans. I've always maintained I'm a lucky SOB when it comes to finding something decent. Here's hoping I get lucky again.
 
Thanks mate, I appreciate it..
 
Stick with what resonates with you and forget about the truth:) makes it all so much easier.. one thing I will say.. I can't imagine the spit that gets directed at any of them.. I know what it like with just being a little nuffer on the web, imagine actually having major cred in the industry.,
 
:passitleft:

Does cannabis help seizures?
Evidence from laboratory studies, anecdotal reports, and small clinical studies from a number of years ago suggests that cannabidiol, a non-psychoactive compound of cannabis, could potentially be helpful in controlling seizures. However, there are conflicting reports in the literature. So far, scientifically controlled studies have not shown definitive proof of the effectiveness and safety of marijuana or cannabis in epilepsy. For example, in 2012, a literature review of clinical studies on cannabinoids for epilepsy could not give a reliable conclusion about the effectiveness of four randomized controlled trials of cannabidiol. Yet in the 48 people included in these reports, no side effects were noted. Conducting studies can be difficult as researchers have limited access to marijuana due to federal regulations and even more limited access to cannabidiol; there are also increased financial and time constraints.
Individual reports of children with refractory (or intractable) epilepsy who have tried cannabis, usually with high ratios of cannabidiol to THC, have reported marked improvements in seizure frequency, including a report describing the results of Charlotte, a girl with Dravet syndrome.
Cannabidiol (CBD): Recently, there have been some open-labeled studies in the U.S. of Epidiolex (a drug derived from cannabidiol or CBD), which is produced by a pharmaceutical company (GW Pharmaceuticals). Epidiolex is a purified, 99% oil-based extract of CBD that is produced to give known and consistent amounts in each dose. The U.S. Food and Drug Administration (FDA) has given some epilepsy centers permission to use this drug as "compassionate use" for a limited number of people at each center. Such studies are ongoing for difficult epilepsies such as Lennox-Gastaut syndrome (in children and adults) and Dravet syndrome in children.
Results from 213 people who received Epidiolex (99% CBD) in an open label study (without a placebo control) were presented at the American Academy of Neurology, April 22, 2015 in Washington DC. Data from 137 people who completed 12 weeks or more on the drug were used to look at how helpful or effective the drug was. People who received the Epidiolex ranged from 2 to 26 years old with an average age of 11. All had epilepsy that did not respond to currently available treatments - 25 or 18% had Dravet Syndrome (DS) and 22 or 16% had Lennox-Gastaut Syndrome (LGS).
Seizures decreased by an average of 54% in 137 people who completed 12 weeks on Epidiolex.
Patients who had DS responded more positively with a 63% decrease in seizures over 3 months.
This improvement in seizures lasted through 24 weeks on the Epidiolex, more often for people with DS than without DS.
In 27 patients with atonic seizures (which are commonly seen in people with LGS as well as other types of epilepsy), the atonic seizures decreased by 66.7% on average.
The responder rate (the number of people whose seizures decreased by at least 50%) was also slightly better in patients with DS (about 55% at 3 months) as compared to patients without DS (50%).
People who were also taking the anti-seizure medication Clobazam (Onfi) seemed to respond more favorably to the Epidiolex with a greater improvement in convulsive seizures than in patients who were not taking Clobazam. The authors suggested that an interaction between Clobazam and Epidiolex may play a part in the differences seen.
14 people withdrew from the study because the drug was not effective for them.
A controlled study on on Epidiolex involving many epilepsy centers is now being done that will compare children with Dravet syndrome or Lennox-Gastaut syndrome taking the active drug with children not receiving the drug.
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If not breeding what the point? To decide you own flavours you want from the strain instead of growing somebody else's choices is one I can think at the moment.. but this is all personal choices and we're all making the right ones at the time. They might change in future but that's life. Thing is not to get to rosecoloured glasses and deny other good shit..
 
TheBlaze said:
So MNS is opensource while guys like GHS and DNA are the microsofts of this world? Ok, I can buy that. It's just frustrating how every breeder has their own version of the "truth". It makes it very hard to figure out who came up with what. As an example, Shanti vs Ingemar. The only thing I'm certain of, is that fans of Shanti's work will naturally defend him as the original creator of white widow. Thing is though, it's impossible to know for sure. So you go trawling the net for some decent examples of black widow, but then can't find any.

Also, if you aren't looking for breeding stock, what is the point? I don't want to drop 6 regs and come up empty handed.

The allure of black widow is strong though! So my next seed purchase will include 6 beans. I've always maintained I'm a lucky SOB when it comes to finding something decent. Here's hoping I get lucky again.
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whoever created it, my money is on shanti, either way he is the only holder of the original parent plants :thumb:

White Widow was originally bred by Shantibaba, the original founder, owner and head breeder of The Green House Seed Company (GHSC). The variety known as White Widow immediately catapulted itself into rock star status upon introduction to the public in 1994. Within a year of its initial release, White Widow took first place at the High Times Cannabis Cup in 1995 and a wave of copy cat White Widow varieties hit the market soon after. In 1996, both Nirvana and Dutch Passion seed companies purchased a single pack of White Widow seeds respectively from Shantibaba himself at the GHSC and within a year released their own versions of Widow. It wasn't long before one would be hard pressed to find varieties of cannabis seed available from Holland that weren't hybrids of the original White Widow released in 1994, literally breathing life into the Dutch cannabis breeding scene that had lagged in the time prior to White Widows release. For many years in Holland varieties such as Northern Lights, Skunk, Afghani and Haze were staples of the Dutch breeding community and with the introduction of White Widow came a renewed vigor in breeding top of the line, commercial and medicinal quality strains of cannabis. With success my friends, breeds greed and contempt for ones fellow man. A wave of White Widow varieties were available to the public by the late 1990's, all of which were either hybrids a selected White Widow variety from a commercially available pack of F1 White Widow seeds from the GHSC, backcrosses from the original Widow or in some cases out right fraudulent lines to begin with. Having no true relation to the original Widow through hybridization or backcrossing. Imposters! To add to the growing complicated Widow landscape of the time, unscrupulous characters such as Ingemar, a former employee of the GHSC and self described breeder emerged claiming to be the true breeder of White Widow, offering their own version of the now legendary strain of cannabis. As if the whirlwind of disinformation wasn't enough, along with Ingemar, yet another man who calls himself "Ecotronics" has laid claim to being the true breeder of White Widow and has been insistent everybody else is making money off of his line. While nothing is ever as black and white as it would seem from the outside looking in, it's this kind of success and ultimately, confusion, that leads to the eventual name change of the original White Widow to the now proverbial Black Widow.

For those of you who may be in possession of genetics related to the Ingemar White Widow, but whom may be finding this article disappointing, I have you covered in that department as well. At one point in time, the man known as Ingemar worked for the GHSC, but if you were to believe Ingemar's own account of the pedigree of his White Widow lines, one is left with the impression we are talking about distinctly different lines of White Widow from that of the Mr. Nice Seeds White Widow aka Black Widow. According to Ingemar, who now proudly assumes the title of "The Father of White Widow", the pedigree of his line of White Widow is a secret, but that it was ultimately created from two seeds found in hand rolled hash which were subsequently selectively inbred for at least six years. Ingemar claims to have had access at the time to acres of land that he used to select the best plants from literally thousands of specimens. Again, the exact criteria Ingemar used to select his plants are kept a secret but he has been quoted as stating feed back from numerous medical users over the years played a role in the selection process of his particular White Widow line. According to Ingemar, the GHSC now uses his White Widow lines with express permission given solely to Arjan to use the name White Widow. In an ironic twist of fate, the GHSC now takes complete credit for the breeding and success of White Widow, without mention of either Ingemar or the true breeder of White Widow, Shantibaba, who of course is the only person in existence today with access to the original mother and father lines that created this now mythical variety of cannabis.

As was mentioned earlier, the pedigree of the Mr. Nice seeds Black Widow is the result of a union between a south Indian hybrid indica and a Brazilian sativa. The south Indian hybrid was found at Kovalum Beach, but it was ultimately cultivated in the surrounding mountainous terrain of Kerala. Shantibaba has stated in the past that the special qualities of the south Indian hybrid were enough for him to schedule a "safari" into the mountains of Kerala to find it on his Enfield bike. Within a few days, Shantibaba found himself "sitting in a café drinking a chai and smoking a joint", when a middle aged, glassy eyed fellow approached him and helped finish off his smoke. After getting severely stoned and drinking the last of their tea, Shantibaba accompanied the man back to his farm only to discover this was the grower of the strain that had lead him into the mountains to begin with. After several days of testing numerous samples of marijuana, all of which had been cultivated, selected and "bred" for years based on resin production, selection was ultimately made on what would later become known as one half of the legendary pedigree of Black Widow. The man who helped Shantibaba finish his joint and ultimately supplied the seed that would later become known as the South Indian hybrid, told him that the seed had always been in his village, but that variation existed among the line depending on which village you visited to gather your wares. The plants are said to finish rather fast, but aesthetic wise have a sativa-esk appearance to them. Along with the Black Widow, several hybrids of this deadly lady have went on to garner much acclaim in their own right, most notably the White Rhino (now known as Medicine Man) and Great White Shark (also known as Peacemaker and Shark Shock), both of which have won a multitude of awards and cups in their own right, with the Medicine Mans pedigree consisting of Black Widow x Afghani and the Shark Shocks pedigree being Black Widow x Skunk#1. These are the original, "true blue" champion lines that garnered the reputations which precede themselves. Both lines find their ultimate pedigree traced back to the original White Widow bred by Shantibaba at the GHSC, now of Mr. Nice seeds (MNS), fronted by the legendary hash smuggler Howard Marks alongside the original "King of Cannabis", Neville Schoenmaker.

It should be noted there are several Widow Hybrids available to the public from MNS, but all varieties containing the name Widow in the description come from either a select male or female cultivar, both from the same generation whom have underwent extensive testing. Hybrids such as Medicine Man, La Nina, G13xSkunk and Shark Shock are all varieties offered by MNS that encompass the Black Widow father as the main building block for their pedigrees. The exact formula of this male is somewhat of a mystery for all but the select few, however extensive breeding was done on the original White Widow (Black Widow) line and the male contains both the South Indian hybrid sativa/indica and the Brazilian Sativa. In very general terms, within a pack of seed of Black Widow one should expect the females to yield somewhere in the neighborhood of 350-400 grams per square meter. Of course it is phenotype dependant, but an experienced grower could probably do better with some time spent working with the line. Outdoors, the plants can be expected to finish by mid-October. Between the major three, Black Widow, Medicine Man and Shark Shock, the Medicine Man is touted as the fastest variety, coming in between mid September and October with the Shark Shock expected right around the beginning of October, give or a take a few days of course. Of all the hybrids however, Shantibaba describes the Shark Shock as the most successful breed of the '90s. One can not go wrong with any of the Widow selections; however the Black Widow is obviously perfect for the amateur breeder. If one was to find themselves in Amsterdam with some time to spare to try each line for them selves, according to Shantibaba the Katsu coffee shop on the Sarphatti Park, along with a gentleman known as Mr. Haze (supplier of official MNS gear to many Dutch coffee shops) and quite a few others stock the MNS Black Widow.

When it's all said and done, at the end of the day, those at Mr. Nice Seeds hold the original parental lines that produced the White strains that won all of the acclaim in the mid to late 1990's. The awards and cups are documented, and exist as irrefutable proof of the true origins of the White Widow line. These varieties of White lines are not nearly uncommon, but are of a quality rarely seen on a consistent basis that have managed to capture the hearts and minds of millions of cannabis enthusiasts the world over. Unfortunately, it is all too easy to be led in the wrong direction when it comes to the quest for the true White Widow. Now the picture should be painted much clearer for you. Though, the search has only just begun. Selection is the key to success with any variety, but with some diligence you too can have a mother plant that produces herb almost too toxic to indulge in on a consistent basis. Heed my warning; this is one of the most powerful varieties of cannabis known to mankind. Handle with care, because these lines are known to leave even the most experienced of smokers pleading for mercy. Good luck out there, friends. However, if you go to Mr. Nice seeds to get your Widow you're not going to need it.
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GrizzWald said:
Stick with what resonates with you and forget about the truth:) makes it all do much easier.. one thing I will say.. I can't imagine the spit that gets directed at any of them.. I know what it like with just being g a little nuffer on the web, imagine actually having major cred in the industry.,
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It shouldn't be like that though. Especially in this industry. The almighty dollar is still king it seems.
 
FeralA9X said:
whoever created it, my money is on shanti, either way he is the only holder of the original parent plants :thumb:
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That's like quoting the bible to a non-believer as proof that God exists. :cheesygrinsmiley:

Anyway, I don't want to piss off 2 of my forum friends in one post, so I will leave it alone by saying that Shanti is a good bet as the original creator. :thumb:
 
:rofl: not going to piss me off bro :rofl: anyone is welcome to believe what they think is the truth, its very shady at best with most things in this industry but Shanti has nothing to hide, he lists the genetic makeup for every strain he has ever created whereas every other person that claims it hides their genetics, why would they need to do that? do they not know? are they trying to hide the genetic makeup so people cant copy it? well its quite easy to self a plant and claim it as your own or do some backcrossing :thumb: even if it was Ingemar that created White Widow, he worked for GHS, who owned that at the time? Shanti ;) either way as I said he holds the parent plants from the cup winners, the most original genetics you can get :thumb:

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As grizz has said many times, you only need to look at their forums and the amount of other well known active breeders on there, people would very quickly lose their shit if they were not getting what was described.
 
A pheno hunting journal would be cool. Get a few guys together all growing the same strain. A cut of black widow that exemplifies all the greatest qualities of the original WW would definitely be worth the effort.
 
That's something I would love to be a part of. Need to get my next seed purchase in then. I'm just a little nervous, as my previous package was ripped open by customs. Strangely though, they didn't open the seed pod. LOL!
 
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