A Base Treatment Regimen For Cancer

KingstonRabbi said:
This goes all the way back to post #449, which is as far as I've read so far.

Analytical360 posts all of its test results online. The THC/CBD levels are posted in long table. Detailed profile of 9 cannabinoids and 9 terpenes is available if you click on each test batch individually. I've been downloading profiles of strains I use to see what makes them work. It takes a long time to do one by one. It would be nice if they would allow access to the full data set to speed things up for us. Werc Labs and others might also share for research purposes.

It's interesting to see how well fixed some strains are and others can hardly be called strains. Dutch Treat has very stable profile across a dozen samples (with 1 outlier), while the classic White Widow has been so adulterated that only a few samples are true to the strain.

I wish I had more time to work on that myself. Nailing down the profiles for medical use has been one of my goals since I started researching MMJ for my own treatment. One of the problems with going by profiles, though, is the entourage effect. Early on I was interested in humulene (still am!) but found other strains high in humulene with very different effects. I was hoping that by adding specific terpenes to CCO I could produce desired effects, but this blessedly confounding plant just isn't that simple!

Still, I agree with cajun that terps are the future of MMJ. :Namaste:
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I still agree, and wish I had more time to devote to it right now, but other priorities insist on being tended to. Try as I might, I can't be everywhere. :laughtwo: I hope you have great success in your research KR. It would ultimately benefit everyone.

That entourage effect.... They threw that one at us so fresh it's still wet behind the ears. Similar to the bantering about of the ECD deficiency disorder that's just now being investigated. Each plant has such an individual profile it's hard to tell what is doing what. This one will take a few more years to nail down.

May I ask, what is it about Humulene that makes it so attractive to you in your particular situation?
 
May I ask, what is it about Humulene that makes it so attractive to you in your particular situation?
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a) I'm a home brewer and hop-head, so natural attraction to humulene.
b) One of the strains that helped during chemo treatments (cinex, for daytime energy) had a high humulene level.
c) I noticed a very pleasant effect combining very hoppy ale with trinity. Now that I've read more about bio bombs I think the effect was due to the alcohol plus myrcene also from hops. Not medical related unless you count stress relief, which I do.

The outcome of my initial investigation was that it's the total profile that matters more than individual terpenes. Some simpler effects are more consistent, but more often it seems to me that terpenes have multiple effects and which ones we feel most depends on what else is in the mix. Kind of like a good gumbo that takes all those individual flavors and transforms them into something completely new and different. It's not a blend of flavors, it's something you only get with gumbo.

Now I want to investigate gumbo so more. :Namaste:
 
KingstonRabbi said:
a) I'm a home brewer and hop-head, so natural attraction to humulene.
b) One of the strains that helped during chemo treatments (cinex, for daytime energy) had a high humulene level.
c) I noticed a very pleasant effect combining very hoppy ale with trinity. Now that I've read more about bio bombs I think the effect was due to the alcohol plus myrcene also from hops. Not medical related unless you count stress relief, which I do.

The outcome of my initial investigation was that it's the total profile that matters more than individual terpenes. Some simpler effects are more consistent, but more often it seems to me that terpenes have multiple effects and which ones we feel most depends on what else is in the mix. Kind of like a good gumbo that takes all those individual flavors and transforms them into something completely new and different. It's not a blend of flavors, it's something you only get with gumbo.

Now I want to investigate gumbo so more. :Namaste:
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I understand, and I agree that it's the natural combination of components in each individual plant that's so profound. I have a theory that the plant picks up on the energy of the grower and produces a profile compatable with that person's needs. I know it's completely impossible to prove, but I've seen too many cases of it happening not to suspect some grander scheme in play that we don't understand. The subtle energy fields we walk around generating are more interactive than we give them credit for IMHO.

For gumbo I suggest you to go talk to Tead. He'd be in his glory discussing the finer points of gumbo. :laughtwo: As an aside and a special treat, may I share with you a link to UncleCannabis's recipie for gumbo?

UncleCannabis's gumbo recipe
 
Here is link to Analytical 360 test results for last 60 days, about 1000. The table only shows THC/CBD, but if you click on strain it will pull up 9 cannabinoid/9 terpene profile. The results are for Seattle area so may not match same strain available in your area or from seed. Also selection is skewed toward local market. Don't think many outside Washington grow UW Purple (go Huskies!). And as stated before, some strains are highly variable so individual tests may not be reliable. A lot of growers trying to cash in on a name.

If you're a data geek like me you should have a lot of fun. Enjoy! :Namaste:

Test Results | Analytical 360
 
SweetSue said:
I understand, and I agree that it's the natural combination of components in each individual plant that's so profound. I have a theory that the plant picks up on the energy of the grower and produces a profile compatable with that person's needs. I know it's completely impossible to prove, but I've seen too many cases of it happening not to suspect some grander scheme in play that we don't understand. The subtle energy fields we walk around generating are more interactive than we give them credit for IMHO.

For gumbo I suggest you to go talk to Tead. He'd be in his glory discussing the finer points of gumbo. :laughtwo: As an aside and a special treat, may I share with you a link to UncleCannabis's recipie for gumbo?

UncleCannabis's gumbo recipe
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I beg your pardon...
I am known by most for my gumbo rather than MMJ stuff.
My gumbo cures anything! Lol.
 
cajuncelt said:
See the name?
I'm from Deep Cajun Country; Breaux Bridge, Louisiana.
My family has won awards for our gumbo mon ami.
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I was counting on that! Hoping to steer some of it my way and put mine to a real test. After all, in a gumbo contest we all win.

Now let's lay this to rest until that someday arrives.

To paraphrase someone important to us all at :420:, Peace Love and Gumbo! :Namaste:
 
cajuncelt said:
I beg your pardon...
I am known by most for my gumbo rather than MMJ stuff.
My gumbo cures anything! Lol.
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Sorry Mon Ami. No offense intended. You're not here that often these days and Tead's been working with me on a project so naturally, he sprung to mind. :laughtwo:

My apologies sir. Your gumbo has already been acknowledged as superior by UncleCannabis, if memory serves. :battingeyelashes: :Love:
 
KingstonRabbi said:
Here is link to Analytical 360 test results for last 60 days, about 1000. The table only shows THC/CBD, but if you click on strain it will pull up 9 cannabinoid/9 terpene profile. The results are for Seattle area so may not match same strain available in your area or from seed. Also selection is skewed toward local market. Don't think many outside Washington grow UW Purple (go Huskies!). And as stated before, some strains are highly variable so individual tests may not be reliable. A lot of growers trying to cash in on a name.

If you're a data geek like me you should have a lot of fun. Enjoy! :Namaste:

Test Results | Analytical 360
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You're a doll KR. Thanks for the link. I need something to distract me. Lost my harvest and found mites in the tent. Not my finest day.

Edit: Good grief KR, this is delicious!! Thanks again. :hugs: :Love:
 
All in good fun.
Most assume I make gumbo cause I'm Cajun.
But, I can't even cook good eggs. Seems you need a lower temp than I'm willing to use. Lol.
If out biggest challenge is gumbo, we're all in pretty good shape I believe!
Good on ya...

P.S. Teads not a stranger to Cajun culture& I know by his recipe he can bang out some roux soup. With all the lagniappe too.
 
cajuncelt said:
All in good fun.
Most assume I make gumbo cause I'm Cajun.
But, I can't even cook good eggs. Seems you need a lower temp than I'm willing to use. Lol.
If out biggest challenge is gumbo, we're all in pretty good shape I believe!
Good on ya...

P.S. Teads not a stranger to Cajun culture& I know by his recipe he can bang out some roux soup. With all the lagniappe too.
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Hahaha! Thanks Cajun. Needed that laugh! :laughtwo: Tead does love to talk food. Lol!
 
Time for me to lay it all out on the table for my treatment plan.

Diagnosis: I have stage 4 head and neck squamous cell carcinoma, HPV positive, met. to lungs.

Status: The tumors are gone from my neck and only 2 very small tumors are visible in lungs as of last scan 6 weeks ago (5 months post chemo.) Next scan is end of this month.

Initial Treatment: Cancer started on tonsils and spread to lymph nodes, which is when it was detected. Initial treatment was daily radiation with weekly chemo. Tumors disappeared and we thought I had beaten it. (sound familiar?)

2nd treatment: After 8 months x-ray found 4 medium sized nodes on lungs. Scan confirmed and found dozen more smaller nodes on both lungs, most in locations of lymph nodes. Biopsy confirmed it was same cancer due to HPV present. Treatment was triple cocktail of chemo (cisplatin and docetaxel every 3 weeks, targeted immuno-drug weekly.) Tumors shrank and most 'disappeared', but as doctor informed me there is still an invisible core at each tumor site that chemo can't reach. No regrowth visible after 5 months.

My activity: First thing I did after terminal prognosis was to research all the phase 3 and 4 trials that might buy me enough time to get to the next big breakthrough. Initially I was optimistic, but gradually reached conclusion that all treatments including the most radical had the same fatal flaw: they tangle up cancer cells so they can't divide and eventually die, but it is slow process and not at all like the normal apoptosis. Metastasized cancer always develops resistance to chemo drugs. Targeted immunotherapy drugs haven't shown they can do much better.
Simultaneously I started researching MMJ. What makes me optimistic is that both THC and CBD induce apoptosis using methods already built into cells. Cajun has thread explaining THC's role blocking ATP production without which cells can't live. CBD starts a protein cascade, which is another system built into cells. Fascinating stuff, sorry I don't have a link to that research anymore.

MMJ use to date: I started using 1:1 FECO (full-plant extract cannabis oil) during 2nd round of chemo. I tried to follow RSO protocol dosing orally 2x per day. Started with grain of rice and slowly built up to gram of oil. Problem was that I still felt too impaired to work as accountant at dosage high enough to treat cancer. I switched to higher THC 2:1 ratio that I tolerated better but still couldn't maintain high dosages.
Since then I've tried tacking with blend of about 8:1 THC:CBD without psychoactive effects. It was limited run experiment because since law change in WA state oil good for medical use is hard to find and much more expensive. Currently I'm out of oil. I will start harvesting from my perpetual grow this week and still arrives Wednesday to start making own oil.
I do still use small doses of both CBD and THC strains for other conditions that I used to take a dozen prescriptions for.

My original plan: Juice the whole plant including buds to extract THCA which is not psychoactive. I have since found that a) THCA does not have same cancer fighting effect as activated THC, and b) even though carboxylic acid attached to THCA is hydrophilic juicing was not very effective at extracting it. I did a test of left-over leaf/buds and made some very potent cannabutter.

New plan with room for improvement:
1) Juice the plant for the health benefits at least from leaves, probably buds too. I don't think much THC is lost as THCA in juicing, but I'm open to everyone's input on this. There is so little data to go on out there.
2) Make oil from leftovers of juicing, dried as if curing whole buds.
3) Use tacking to build up to maintenance level daily dosage of 200-300 mg total. I will try to dose 5x day this time around.
4) Eventually add suppositories to increase to full gram/day dosage. If next scan shows any growth I'll add this immediately.
5) Continue working as much as I'm able, because being able to work is part of my healing process.

The strains I'm growing now are mostly THC: Dutch Treat, Chernobyl, White Widow, Black Cherry Soda, Critical. I also have Hash Bomb, which is 5+% CBD and 15% THC.
I have ordered 2 indica THC strains (K-Train, Blue Mystic) because I've read purer indicas are better for cancer. Not sure about that but want to cover all bases.
Also ordered 2 1:1 strains (Dance World, Medical Mass) because I want to hit from as many angles as possible.

I welcome suggestions on any part of this plan. Because this is stage 4 metastatic cancer I want to nail down details as tightly as possible.

Thanks to everyone for all the posts that have motivated me and helped me pull this together. You are my dream team. :circle-of-love: :Namaste:
 
I think your plan is spot on. Juicing, tacking, Bio-bomb,Suppositories( which imo is a must), numerous strains in different combinations. I used a similar protocol with a lady who treated her Lung cancer and Copd with success. My harvest is just around the corner, Blueblood, bubba kush, blue shark, Lsd, violator kush, purple kush/headband & Black Destroyer. 10 lbs which much of it will be used to help others. Kinda of sucks ya got to be incognito in illegal province along with a small town.
 
I'll post more later & the scientific/test info.
It looks like there are some products that are great substitutes for liquid lecithin.
There is info that "it" has actually reversed specific cancers several survivors.
I'll posting now, so I remember to come back.
 
cajuncelt said:
I'll post more later & the scientific/test info.
It looks like there are some products that are great substitutes for liquid lecithin.
There is info that "it" has actually reversed specific cancers several survivors.
I'll posting now, so I remember to come back.
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Thanks mon ami, and good to see you again stranger. :hugs: We hope all's well with you.

This is pretty exciting stuff you dangled there. I'll be watching :battingeyelashes: :Love: Is the "it" you refer to liquid lecithin or some other product?
 
panacea said:
how do ya post a pic off of your iphone 5s? Sweetum's? lol
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I'm using an iPhone 6 now, but the process is still the same. I actually find it easier to load from the phone because it remembers the gallery and doesn't make me choose it again every time. I keep a window open for each gallery. It's basically the same process as with the iPad - pull up the gallery, choose photo library and pull the photo from the camera roll.

Was that clear enough? The have to be loaded in one at a time, unfortunately, but the phone has intuitive text, so it's a step ahead of me and I usually only have to type in one letter before it give me the proper option.
 
KingstonRabbi said:
Oh, one more thing. There will be Gumbo! You're all invited to my place for Fat Tuesday, if not sooner.
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I'll be there with bells on. Lol! When I relocate to the west coast as planned maybe we'll make that gumbo happen. Lol!

Thank you for that wonderful write-up of your situation. I agree with panacea, you've thought this out after extensive research. I applaud the time and effort you've put into this. I understand this is your life we're talking about, but that doesn't always translate into the focus you've demonstrated. Your understanding of the process makes all this easier to approach.

You're off to a great start KR. What specific input are you hoping for from us, because it looks to me like you're already on it.
 
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