So a little background about me and Maryjane. I have Chrons Disease and I have to say it has been the best medicine for me. When I use prescription meds (pills from the Dr.) for pain and for regulation of my condition I've noticed minimal change if any when taken without my herbal meds. when I take my herbal meds alone I fell 100% better. No flare-ups at all. Now im not a Dr or have any scientific data to back up my results I just know how I feel. I personally dont think that it is or should be a substitute to my meds but it should be used with them.