It's something I've thought about a few times over the years. I'd have to setup a drip feed system for them I think, as I can't be in there watering all the time but I've got all the bits to do that already. The other thing is issue with paranoia on plant count. I fear if I was unlucky enough to get my door kicked in they'd say 8 plants with the potential to produce 4 zillion pounds worth of mind altering super skunk.
I've got so many seeds a couple of runs from seed wouldn't be a problem. I like variety too so I'd have to keep at least 2-3 bonsai mothers if I wanted to do clones.