I think I have dodged the dreaded root rot. More through luck I think, though I did change my DWC res completely every 3-4 days for the longest time lol.
As for the missus, she has had a trebeculectamy in each eye which is keeping her pressures stable at the moment (shes already totally blind in her left eye as her previous optician did not diagnose her glaucoma until it was waaaay too late) but she is adament that when the trebeculectamies stop working (she's been told that in all likely hood they'll eventually be ineffective - no idea why) she does not wish to go back to the drops she was on before. I met her after her eye surgeries were done but from how she describes the drops I dont blame her for not wanting to take them. I dont know which particular drops it is she hates, I'll have to ask her when she's home. She just started a night shift so I'm flying solo with the baby at the mo. You are correct from everything we understand about it you need to constantly dose every 4 hrs or so, depending on how long your selected method of consumption lasts. Smoking has a faster initial effect but lasts a lot less time. Ingesting is the best way to make the doses last the longest time possible. She just wants there to be bud on hand in case of her operations ever failing. She doesnt touch it otherwise. Its me that is the heavy user, I have it for back pain and anxiety (not here to lie, I enjoy it recreationally also).
Im sorry to hear you suffer with glaucoma too, I hope I can be of some more use when the missus is around.
Edit: thinking about it, they can make slow release nicotine patches for smokers...maybe they can come up with something similar for glaucoma patients with weed. Slap one on and you are good for 8hrs, atleast you could get a normal nights sleep then.