Reads like marketing hype to me Oldbear. Did you get that feeling?
It's interesting to read the way they skew the data and use straw man arguments to sell their product. For example, no one says that curing is decarbing except they are so they can disprove it. They say there's no difference in decarbing fresh and dried bud except "in the right conditions" and "in a controlled setting." Whose controlled setting? Theirs! They say you can't decarb in an oven at 220º for 40 minutes. How about 240º for 60 minutes? They don't say. Here's another one: "Fact: Fats and alcohol aren’t needed [empasis theirs] in order to decarb or administer cannabis, but they can be useful to pair with activated cannabis to aid in digestion and absorption." Another straw man. No one says infusing cannabis with alcohol or fats decarbs them, and no one says you have to use fats to administer cannabis. It's just better that way! Oy.
I don't think their average reader has our background. Lol! Thanks for that Oldbear and Shed.
Shed, a while back you asked me how the body produces cannabinoids. I've been mulling it over for a while and I think I'm ready to toss it out there.
The way I think it works:
I'm coming at this from a gut instinct as much as science. I'll admit that up front, because the reality is I'll see what I'm looking for. I do my best to pay attention to what the science is trying to show us, keeping in mind that so much of the science is slanted to show the perceived or fabricated evils of THC and/or strapped by inadequate supply of research material that matched what we all consume.
There are some things we know about endocannabinoids.
* When a cell is stressed the chemical environment of that cell is effected. The ECS responds by pulling lipid molecules from the cell membrane and combining them with other molecules to create a particular endocannabinoid.
Omega 3s are the molecules the ECS is pulling from the membrane, the building blocks of endocannabinoids.
The newly-created cannabinoid activates a receptor on the cell membrane. The resulting chemical cascade inside the cell changes the cellular environment, and if all works as planned, the cell goes back to its homeostatic state. Balance is restored.
On demand, on site, instantly produced, utilized, and then disassembled by the enzymes in preparation for removal by the clean-up crew. In less time than it took to blink.
Continuing with the exploration we find:
* The ECS creates receptors in the CNS that migrate to peripheral cells. As need arises for more receptors, the ECS responds by creating them and shipping them out. This is particularly useful in pain modulation, which is where I learned about it.
Switching to instinct:
I think it has something to do with vibration. Purely speculation on my part, but it makes sense to me. A healthy cell vibrates a particular tone, and a community of cells in homeostasis maintain a particular tonal range.
The activity of receptor activation is a change of vibration, which causes a series of cellular modifications across a broad spectrum.
So my theory is that the cell out of vibration sets off an alert that triggers the creation of the endocannabinoid that'll signal the modification that resets the cellular vibration back to an acceptable range. It seems obvious to me that an increase in stress, coupled with a degradation of nutritional intake creates a cellular atmosphere challenging to a healing force that appears to respond more positively to joyfulness.
Science shows us that the cells know how to heal. My simple message: You are evolved to spontaneously heal. Joy may be your greatest healing tool.
@medmanmike, the infusion percentage isn’t a decarboxylation rate, it’s an extraction efficiency rate. Different values. Most decarb before infusion, and that decarb percentage would carry through. The extraction efficiency ratebtells you how many of those available cannabinoids you’ll recover.
A lot has changed since we started this adventure. This thread was a brainstorming effort and much of what we learn gets developed into other medical threads.
Pass it this way - please!
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That sound would be wheep, wheep