I'm currently doing a side by side by going by VPD char and not.
Both rooms are at same temps - 27c daily and 25 @ night.
One room is at 50% humidity, the other is 75 humidity.
Both rooms with same nutes, CO2 supplement @ 1100 PPM.
Same strain - Critical 2.0
So far, from the veg I can safely say that higher humidity works WAY better so if you can do something about it, especially the first 3 weeks in flower, trust me you will be satisfied.
However, higher humidity brings more pests so I use a.r.t.s granulaat @ 20g each pot, its a bio insecticide against worms and larvaes cause fungus gnats are the most common problem, but I had mites too.
I found out, spraying bi-weekly with Neem (i know once/week can work aswell but im a maximalist person) will prevent any kind of pest attacks.
I also have sulfur burner that I burn weekly.
I follow this chart
Veg: 81 F, 70 RH, 1000 ppms
W1-3: 81 F, 70 RH, 1000 ppms
W4: 81 F, 65 RH, 1000 ppms
W5-6: 78 F, 60 RH, 1000 ppms
W7: 75 F, 55 RH, 400 ppms
W8-8.5: 75 F, 55 RH, 400 ppms, RO flush
Hope this information helps you some way or another, good luck.