A Base Treatment Regimen For Cancer

[Dave Groomer]

Re: any info on toxicity in pregnancy

Any info? Thanks!

There is a study sited in Jeff Ditchfield's book "The Medical Cannabis Guide Book" that was done on pregnant women in Jamaica that used cannabis one year after birth their children's birth. It was published in "The American Journal of Pediatrics" in 1994. It showed that the children of the women that used cannabis on a regular basis during pregnancy were:

Higher quality of alterness
Motor and autonomic systems were more robust
They were inclined to be less irritable
They were less likely to demonstrate imbalance of tone
They required less examiner facilitation to become organized
They displayed better self-regulation
They were more responsible and autonomically stable

 

[SweetSue]

Re: any info on toxicity in pregnancy

Any info? Thanks!

Deborah, there's anandamide in breast milk. Cannabinoids are a natural expression of the human body, your body's healing force. This dynamic system exists to enhance our physiology. The propaganda wars were effective, but seriously flawed by the desperate need of others to control what they still don't understand.

There is nothing harmful about cannabis. Period. Cannabis use spared me the horrors of early pregnancy when nothing stayed down. It calmed me in late pregnancy when that baby wouldn't sit still. Lol! Responsible cannabis use during pregnancy is something I've always recommended. Neither of my children had any part of their development stunted by my daily use of cannabis during my pregnancies. I've yet to come across a case of any damage to a fetus from cannabis use.

 

[KingstonRabbi]

Yeatster, thank you and the same for your mother. This is the hardest time of my life.

My mother is in CBD 27% and 4% THC orally, and she say that she is sleeping better at night. But she is still in pain. I'm getting a stronger THC oil (66%) of 10 ml this week, and in 14 days a very strong 80% THC RSO. I will make suppositories out of the strong oil.

Question to SweetSue and KingstonRabbi.

The Biobombs, is that just the suppositories or another capsule my mom should take? And do you think it’s okay that my mother takes the CBD 27% orally and the strong THC oil vaginal and rectal? or should I'll make a mix of CBD and THC in the suppositories?

About the dosage of the suppositories. Should my mom start with a mix of 20:1? 20:1, is that a mix of CBD and THC or mix of coconut oil and THC?
20:1, does it mean 20 mg of CBD/coconut oil and 1 mg of THC? Or just 20 times to 1?
Do you know where I’ll can buy some good Apigenin pills and Amentoflavone. Can’t find it here in Denmark.


Thanks

Kristian

Bio Bombs are the mixture of cannabis oil and carrier oils that use in the suppositories or can use in edibles. The 20:1 ratio to start with is 1 part cannabis oil to 20 parts carrier oil. I increase the ratio as I progress but keep the total volume at 21 units. for example, next step up would be 2:19, then 4:17, 8:13, and then a couple steps up to 18:3. You don't have to hit those ratios exactly, just in general increase CCO with each step.

You can use coconut oil as carrier oil, but extra virgin olive oil or flax seed oil are much better for avoiding breakdown by the liver.

Next step is to mix with more carrier oil plus liquid lecithin. 45 units of carrier oil, 15 of liquid lecithin. total volume is 81 units. If you use ml as base unit you will end up with 90 capsules per batch which is more than you need at low doses. Use a small oral syringe to measure 1/4 ml of cannabis oil and adjust the other oils in proportion. At higher doses I spent about 2 weeks at each level and 90 capsules was a little more than I needed but it was nice to have the extras to back off from the next higher dose temporarily if I wasn't quite ready.

I get my apigenin from Swansons online. I use ginko extract for the amentoflavone.

After I completed the first batch it became much clearer to me how it all came together. 20:1 mix plus additional carrier oil and lecithin made 00 size capsule containing 10 mg cannabis oil each. Next step was 20 mg. 18:3 plus same amount of additional carrier oil/lecithin made 200 mg capsules, which is highest you will need for 5 doses per day to reach 1 gram.

Don't worry if you need us to walk you through it a couple times. As long as first batch is low and you increase consistently you will get it right.

I would use both THC and CBD oils in the bio bombs taken rectally/vaginally for maximum effectiveness.

 

[Dave Groomer]

Dr. Oliveres & I were interviewed by InfoWars & WBAP this morning. We won't be the "feature", but a segment on my clinic will be aired towards the end of March.
My 15 minutes of fame.
I see the A-Team stepped up to field new members questions here. Thank you.
It seems there are some own ended issues floating around a lil still?
I'll jump on here Tuesday if I can & answer them & see if I can help out or add anything useful.
I hope y'all are all doing well. Miss you freaks. Lol.

Oh, real quick... You don't need mold for supps. I'll explain better later. Thanks for the patience.

Post a link when there is one so we can watch!!!

 

[Pman1983]

Bio Bombs are the mixture of cannabis oil and carrier oils that use in the suppositories or can use in edibles. The 20:1 ratio to start with is 1 part cannabis oil to 20 parts carrier oil. I increase the ratio as I progress but keep the total volume at 21 units. for example, next step up would be 2:19, then 4:17, 8:13, and then a couple steps up to 18:3. You don't have to hit those ratios exactly, just in general increase CCO with each step.

You can use coconut oil as carrier oil, but extra virgin olive oil or flax seed oil are much better for avoiding breakdown by the liver.

Next step is to mix with more carrier oil plus liquid lecithin. 45 units of carrier oil, 15 of liquid lecithin. total volume is 81 units. If you use ml as base unit you will end up with 90 capsules per batch which is more than you need at low doses. Use a small oral syringe to measure 1/4 ml of cannabis oil and adjust the other oils in proportion. At higher doses I spent about 2 weeks at each level and 90 capsules was a little more than I needed but it was nice to have the extras to back off from the next higher dose temporarily if I wasn't quite ready.

I get my apigenin from Swansons online. I use ginko extract for the amentoflavone.

After I completed the first batch it became much clearer to me how it all came together. 20:1 mix plus additional carrier oil and lecithin made 00 size capsule containing 10 mg cannabis oil each. Next step was 20 mg. 18:3 plus same amount of additional carrier oil/lecithin made 200 mg capsules, which is highest you will need for 5 doses per day to reach 1 gram.

Don't worry if you need us to walk you through it a couple times. As long as first batch is low and you increase consistently you will get it right.

I would use both THC and CBD oils in the bio bombs taken rectally/vaginally for maximum effectiveness.

Dear KingstonRabbi, thank you so much for helping me.

Let us cook this down.

We have 90 ml of 27% CBD/4% THC and tomorrow I'll will get 10 ml of 66% THC Indica. In two weeks, we will get a very strong RSO of 80% RSO on Indica (50 ml).

My mother is eating 1.5 ML of the CBD oil before night, without any problems.

So I'll understand that I should make the suppositories of 21 unit total. But what is 1 unit? What is the scale?
We should use extra virgin olive oil, instead of coconut oil, but will the suppositories be hardened? or should I'll put in some cocoa butter?


You advise us to mix the suppositories with the THC and CBD but is that 50/50 1:1? How much is that? in mg or ml? I'm sorry but I'm not sure in the scaling part :\

Should we make three suppositories with same scaling of oils and the she should step up every third day? She should end up getting 1G of strong THC in 60 days right?

When should we start to mix in lecithin? When my mother is taking 1G of THC per day?

Should my mother just take suppositories and no orally?

I'll can't find Apigenin tablets here in Denmark but will Chamomile tablets do the trick?


Thank you so much.

Kristian

 

[SweetSue]

Alright Kristian, let's see if I can answer some of this with you.

Dear KingstonRabbi, thank you so much for helping me.

Let us cook this down.

We have 90 ml of 27% CBD/4% THC and tomorrow I'll will get 10 ml of 66% THC Indica. In two weeks, we will get a very strong RSO of 80% RSO on Indica (50 ml).

My mother is eating 1.5 ML of the CBD oil before night, without any problems.

So I'll understand that I should make the suppositories of 21 unit total. But what is 1 unit? What is the scale?
We should use extra virgin olive oil, instead of coconut oil, but will the suppositories be hardened? or should I'll put in some cocoa butter?

The basic mix will always come out to 21 ml, regardless of the strength of the cannabinoid load. Then you add the additional 45 ml of carrier oil and 15 ml of lecithin to end up with 81 ml total meds to put into the capsules. This is why we recommend you start with a partial batch, because you'll be increasing every 4-7 days or so, depending on how well she tolerates the increase.

If you do a partial batch you won't be left with a pile of expensive capsules you won't be using when you increase. We can walk you through that if need be. We have great patience. We've been through this overload of information ourselves and we know how frustrating it can become.


You advise us to mix the suppositories with the THC and CBD but is that 50/50 1:1? How much is that? in mg or ml? I'm sorry but I'm not sure in the scaling part :\

You want to come as close as possible to an even ratio, with any slant to the THC, because it's the THC that's doing much of the cancer fighting that we can see. What we mean by that is the percentages of the THC and CBD components found in the oils. And when we say "as close as possible" that's exactly what we mean. Don't beat yourself up if you can't get to an even ratio. In an extreme situation we use what we have available to begin and do our best to work towards better balance.

I'm assuming the RSO you'll be acquiring has a THC value of 80%. Is it possible to determine what value of CBD is in that oil?

Should we make three suppositories with same scaling of oils and the she should step up every third day? She should end up getting 1G of strong THC in 60 days right?

We recommend three to four doses a day. You want to keep constant pressure on the tumor cells, and the cannabinoids begin to degrade or be eliminated from the system within 5-6 hours, according to current understanding.

When should we start to mix in lecithin? When my mother is taking 1G of THC per day?

From the very beginning you'll be adding the lecithin.

Should my mother just take suppositories and no orally?

The big difference is that oral meds will make her euphoric. How much euphoria can your mother comfortably live with. You're talking very high levels of THC. She'll also be tacking just a small bit before every dose, regardless of method of administration. The tacking primes the pump for the major dose.

I'll can't find Apigenin tablets here in Denmark but will Chamomile tablets do the trick?

Excellent choice. Chamomile tea is a wonderful, relaxing treat as well. If she has a taste for the herb I'd recommend regular cups. One of my favorite treats. I think I'll make some now.

Thank you so much.

Kristian

I hope that helped. KR will be here shortly to add his two cents worth. Keep asking until you feel confident. We understand how crazy it is the life threw you into the position of trying to help your mother heal. Nowhere in your life did you anticipate this. We'll do our best to lighten the anxiety.

 

[SweetSue]

I recently came across this article by Under The Tree Biopharmaceuticals, and I believe it belongs here.

The link to the site Treating Breat Cancer With Cannabis: Why The Treatment Must Match The Classification

Article by UPG

Breast cancer is a major and growing health issue among women. Invasive breast cancer is the most common type cancer affecting women worldwide, and the second-most-common type overall, according to the Susan G. Komen foundation. This year, an estimated 232,000 cases will be diagnosed just in the US. Early detection and successful treatment are crucial for survival.

Numeorus Studies show that cannabinoid receptors are over-expressed in the tumor cells of certain cancers, such as cancers of the liver, lung, prostate and breast. Thus, researchers have been led to believe that the endocannabinoid system may be up-regulated in cancer in an innate biological effort to fight off this disease.

Studies also show that when cannabinoids are administered and bind to these receptors, they are able to inhibit cancer cell growth by preventing the proliferation of cancer cells and by inducing cancer cell death (apoptosis). Furthermore, cannabinoids have been found to impair both tumor angiogenesis – the increase in localized blood flow induced by tumor cells – and metastasis – the spreading of cancer to other organs.

CANNABINOIDS AND BREAST CANCER

There has been great medical advancements in breast cancer in recent decades, but certain breast tumors continue to be resistant to conventional treatments. Breast cancer is comprised of tumors that are distinct in their molecular profiles, leading medical professionals to categorize the disease into 3 main subtypes.

Research suggests that synthetic cannabinoids and phytocannabinoids (mainly THC and CBD) may be useful in treating all 3 subtypes of breast cancer, with the strongest evidence of therapeutic potential pointing to treatment of HER2-positive and triple-negative breast tumors. The therapeutic potential of cannabinoids is particularly important for patients with triple-negative breast cancer, as there is no standard therapy that currently exists and prognosis for this group of patients is poor.

In addition to their anti-cancer effects, research also shows that cannabinoids are considerably safer and less toxic than conventional treatments. Cannabinoids are non-toxic to non-tumor cells and are well tolerated by patients – only eliciting relatively mild side-effects such as dizziness and fatigue.

“This compound offers the hope of a non-toxic therapy that could achieve the same results without any of the painful side effects.” – Dr. Sean McAllister

In 2007, Dr. Sean McAllister and his team of researchers were one of the first to discover that CBD’s cancer-fighting properties could be successfully applied to breast cancer.

As it turns out, cannabinoids can provide a variety of other benefits in the treatment of cancer, including the prevention of nausea and vomiting associated with standard chemotherapeutic treatments and reduction of cancer-associated pain. Research also shows that, when combined with conventional cancer treatments, cannabinoids are able to induce a synergistic action against cancer and tumor cells, suggesting that the combination of conventional and cannabinoid-based treatments may more powerful than the administration of either treatment alone.

CLINICAL APPLICATIONS: THE CURRENT STATE

Scientific research on the effects of cannabinoids on breast cancer has been limited to preclinical trials involving cell cultures and animal models. Researchers believe that further preclinical trials are necessary to identify which patient population is the most appropriate for cannabinoid treatment and which cannabinoids specifically present the best therapeutic option for patients before trials can advance to the clinical stage.

Until these factors are established, it is unlikely that oncologists will be willing to prescribe cannabinoid-based medicine for the treatment of breast cancer, despite the fact that research authors continue to assert the need for health professionals to be aware of cannabinoid research.

In a update (2013) published in the Oncology Nursing Forum, associate editor Susan Weiss Behrend concluded:
“…cannabinoids have demonstrated anti tumor activity in preclinical breast cancer models. Practicing oncology professionals need to be aware of the clinical potential of these agents…” – Susan Weiss Behrend, RN

According to doctors and patients we have worked closely with, breast cancer tumors can be effectively treated with cannabis oil. However, they caution, the ratios of the tumor-busting cannabinoids THC and CBD must be matched to the classification of breast cancer—with certain kinds of breast cancer, namely those that are estrogen-positive, the tumor will actually grow if too much THC is used.

Although there are many types of breast cancer, they are usually grouped into four categories, depending on how they show up on diagnostic tests:

Estrogen receptor positive (ER+) or progesterone receptor positive (PR+): About two in three cases of breast cancer (more in older women) have receptors for one or both of these hormones.

HER2/neu (a.k.a. HER2 or ErbB2): HER2/neu is a protein that is over-copied by certain types of breast cancer. HER2-positive cancers spread more rapidly than other types of cancer.

Triple negative: These breast cancers do not have estrogen or progesterone receptors and don’t show overproduction of HER2. Triple-negative breast cancers spread aggressively because they don’t respond to hormones or drugs that target HER2, but chemotherapy is an option.

Triple positive: These types of breast cancer are ER+ and PR+, and they have too much HER2 production. They can be treated with hormones, HER2 drugs, and chemo.

Research has shown that PR+, HER2-positive, and triple-negative breast cancers can be effectively treated with cannabis. The protocols recommended by doctors we work with tend to have high THC-to-CBD ratios, often around 4:1.

Cancers that involve estrogen, however, may actually spread in response to large amounts of THC. Patients with ER+ or triple-positive breast cancer do better with lower ratios of THC to CBD—a ratio 1:1 or 1:3 is preferable, according to doctors and patients we’ve spoken with.

This recommendation comes from doctor and patient experience, not from clinical evidence. Although we have been unable to find any research on this, UPG is hearing from doctors, nurses, and patients that these dosages are best for treating these different types of breast cancer.

Do not forget to schedule your regular check-ups with your doctor.

 

[SweetSue]

I've always wondered if the high incidence of breast cancer in women could be attributed to this insane idea we have that women must bind their breasts to avoid making others uncomfortable with the idea that we have breasts. I really believe you can track breast cancer to wearing of bras from a young age. Geez, I know women who sleep in them. This idea we've placed in the minds of our girls that there's something wrong with the fact that someone could decern a nipple line through the clothing. Couple that with the sense that you're not enough or too much and you have a prescription for low-level self-loathing that can only contribute to the mindset that allows cancer to spread.

It's a stylistic imperative I've resisted most of my life, and any time I've worn bras it reinforces this idea I have that were doing this to ourselves. Social insanity run amok.

Stepping off that soapbox now.

 

[420]

Personally, I think it has to do with chemically produced and stored meat, sugar and dairy consumption along with the plethora of chemical beauty products normally used all over the body, as well as tampons inserted into the body, as well as pads. Shampoo, hair conditioner, soap, hairspray, gel, makeup, lotion, all of it. Then again, chemicals in the bra fabric could also be a contributor. ..


Sent from my iPhone using 420 Magazine Mobile App

 

[SweetSue]

Personally, I think it has to do with chemically produced and stored meat, sugar and dairy consumption along with the plethora of chemical beauty products normally used all over the body, as well as tampons inserted into the body, as well as pads. Shampoo, hair conditioner, soap, hairspray, gel, makeup, lotion, all of it. Then again, chemicals in the bra fabric could also be a contributor. ..

Sent from my iPhone using 420 Magazine Mobile App

I agree. All this focus on making a perfectly acceptable human body "better" and to what end. Hair dye causes arthritis, and I believe it's tied to the belief that we aren't acceptable without it. How ludicrous, and how sad. I'm as guilty as the next one with diet, so I have to step aside. The infected salivary gland I'm healing at the moment can be directly pinned to the excessive sugar consumption of the previous week. I think I finally learned that lesson.

It's not the chemicals in the fabric that concern me, it's the unrelenting pressure you put on the breast complex, compounded by the mind game we play that our bodies have to be "controlled." Obviously, I'm not a woman who trods the heavily-trafficked path. It's always saddened me that we don't encourage our daughters to accept themselves just as they are.

 

[KingstonRabbi]

Sorry, somebody mentioned boobs... er, I mean breasts... and I got a little distracted.

Actually I think society's awkwardness with perfectly natural female anatomy stems from adolescent boys. When breasts start to appear boys notice, and whenever they notice anything they tease mercilessly. They tease each other mercilessly too, but their hormones destroy much of the area of brain that deals with empathy and sensitivity while women actually become more empathetic and more vulnerable. Actually as teacher and now father of 4 girls I've seen girls go after each other even more viciously than boys do.

Madison Avenue has learned to exploit these vulnerabilities into profits. i'm going way beyond breasts or cancer and getting pretty agitated so I'll stop now. Let me close by quoting the motto of the Evergreen State College Geoducks (pronounced gooey ducks):
Omnia Extares, Let it all hang out!

 

[KingstonRabbi]

Kristian, I think Sue did a pretty good job answering your questions. I'll focus on calculating dosages.

If you mix the 2 oils you have now equally you will get mixture that is 14% CBD and 35% THC, or 49% total cannabinoids. That's a little low so you can make first batch a little stronger with more CCO per batch.

Base unit for full batch is ml. I would go ahead and make full batch at 4 ml CCO to 17 ml olive oil, then add the additional 45 ml olive oil with 15 ml liquid lecithin, to make total 81 ml and fill the capsules, about 90 or so. Don't worry, you'll be able to use all of them.

Start by dosing rectally only, not vaginally, 1 capsule 5 times a day (30 minutes after taking the supplements).

After 4 days if she feels ready then increase to 1 rectally and 1 vaginally. I have no experience with vaginal suppositories. It's mucosal membrane so will be absorbed well, but may cause some euphoria. Theoretically it shouldn't. If it does and she's uncomfortable with it you can instead do 2 capsules rectally. With practice you can get them side by side just past the sphincter. Be careful not to push one up too far or she may get euphoria.

With the next batch you can increase both dosages at once or the one rectally first and other after you run out of lower dosage pills. Whatever she is comfortable with. By that point it will become intuitive. Just increase when ready.

Last thing on supplements. Chamomile tea has some apigenin but not much. I found 50 mg capsules online from Swansons. Alternatively you may find product called Amentomax where body building supplements are sold. It contains amentoflavone which is another good competitive inhibitor.

Relax (as much as you can right now) and know that just starting the process will start helping mom, and as you proceed it will quickly become much easier.


p.s.: When you use up 66% THC just continue same with 80% oil.

 

[SweetSue]

Kristian, I think Sue did a pretty good job answering your questions. I'll focus on calculating dosages.

If you mix the 2 oils you have now equally you will get mixture that is 14% CBD and 35% THC, or 49% total cannabinoids. That's a little low so you can make first batch a little stronger with more CCO per batch.

Base unit for full batch is ml. I would go ahead and make full batch at 4 ml CCO to 17 ml olive oil, then add the additional 45 ml olive oil with 15 ml liquid lecithin, to make total 81 ml and fill the capsules, about 90 or so. Don't worry, you'll be able to use all of them.

Start by dosing rectally only, not vaginally, 1 capsule 5 times a day (30 minutes after taking the supplements).

After 4 days if she feels ready then increase to 1 rectally and 1 vaginally. I have no experience with vaginal suppositories. It's mucosal membrane so will be absorbed well, but may cause some euphoria. Theoretically it shouldn't. If it does and she's uncomfortable with it you can instead do 2 capsules rectally. With practice you can get them side by side just past the sphincter. Be careful not to push one up too far or she may get euphoria.

With the next batch you can increase both dosages at once or the one rectally first and other after you run out of lower dosage pills. Whatever she is comfortable with. By that point it will become intuitive. Just increase when ready.

Last thing on supplements. Chamomile tea has some apigenin but not much. I found 50 mg capsules online from Swansons. Alternatively you may find product called Amentomax where body building supplements are sold. It contains amentoflavone which is another good competitive inhibitor.

Relax (as much as you can right now) and know that just starting the process will start helping mom, and as you proceed it will quickly become much easier.


p.s.: When you use up 66% THC just continue same with 80% oil.

A note to Kristian and anyone reading this thread: if what I say and what KR says conflict in any way, listen to him first. I research and assist, he lived through the experience. At many levels we're all lab rats and our egos got left outside long, long ago. I don't think mine would recognize me anymore.

 

[Duarte]

Where can I get information about your clinic?

 

[Pman1983]

Kristian, I think Sue did a pretty good job answering your questions. I'll focus on calculating dosages.

If you mix the 2 oils you have now equally you will get mixture that is 14% CBD and 35% THC, or 49% total cannabinoids. That's a little low so you can make first batch a little stronger with more CCO per batch.

Base unit for full batch is ml. I would go ahead and make full batch at 4 ml CCO to 17 ml olive oil, then add the additional 45 ml olive oil with 15 ml liquid lecithin, to make total 81 ml and fill the capsules, about 90 or so. Don't worry, you'll be able to use all of them.

Start by dosing rectally only, not vaginally, 1 capsule 5 times a day (30 minutes after taking the supplements).

After 4 days if she feels ready then increase to 1 rectally and 1 vaginally. I have no experience with vaginal suppositories. It's mucosal membrane so will be absorbed well, but may cause some euphoria. Theoretically it shouldn't. If it does and she's uncomfortable with it you can instead do 2 capsules rectally. With practice you can get them side by side just past the sphincter. Be careful not to push one up too far or she may get euphoria.

With the next batch you can increase both dosages at once or the one rectally first and other after you run out of lower dosage pills. Whatever she is comfortable with. By that point it will become intuitive. Just increase when ready.

Last thing on supplements. Chamomile tea has some apigenin but not much. I found 50 mg capsules online from Swansons. Alternatively you may find product called Amentomax where body building supplements are sold. It contains amentoflavone which is another good competitive inhibitor.

Relax (as much as you can right now) and know that just starting the process will start helping mom, and as you proceed it will quickly become much easier.


p.s.: When you use up 66% THC just continue same with 80% oil.

Thanks again KR and SweetSue,

I'm more confident in this now.

Yesterday my mother was inlaid to the hospital. She had bleed alot from her virgina over the night. Her platelets in her blood, was very low (thrombocytopenia). So now they are giving her platelets.

The doctors won't give her blood thinners, in the next couple of days. Maybe the mix of blood thinders and CBD oils was too much.

So do you still think we should mix CBD and THC to a start? As I'll understand THC does not have a blood thining effect. CBD has that effect.

But thanks for your answers. We will make the gele capsules tomorrow with CCO and carrier oil of olive oil. Later on we will make supposotories. But do we need to use cocoa butter? They won't be hard if just using olive oil?

My mother should get the THC ASAP :\


Thanks

Kristian

 

[SweetSue]

Thanks again KR and SweetSue,

I'm more confident in this now.

Yesterday my mother was inlaid to the hospital. She had bleed alot from her virgina over the night. Her platelets in her blood, was very low (thrombocytopenia). So now they are giving her platelets.

The doctors won't give her blood thinners, in the next couple of days. Maybe the mix of blood thinders and CBD oils was too much.

So do you still think we should mix CBD and THC to a start? As I'll understand THC does not have a blood thining effect. CBD has that effect.

But thanks for your answers. We will make the gele capsules tomorrow with CCO and carrier oil of olive oil. Later on we will make supposotories. But do we need to use cocoa butter? They won't be hard if just using olive oil?

My mother should get the THC ASAP :\


Thanks

Kristian

I would say the blood thinners were too much. It's more common than you'd think Kristian. I'll let KR tend to the question of mixing the oils, but my gut reaction is you want both together. The synergistic effects of the two components together is so far superior to when used alone that it's almost a waste not to combine them. You're still trying to get the ratios as close as possible.

Don't worry about the cocoa butter and making suppositories with forms. Use the capsules as suppositories. That way you can use olive oil as the carrier. The capsules themselves give the stability needed for insertion. Cajun himself shared this little tidbit with us recently, although he hasn't elaborated yet. That's one very busy man these days.

The capsules work well as suppositories.

 

[KingstonRabbi]

You said you were using 1.5 ml per day orally. The mix of oils I suggested has much less cbd and shouldn't cause problem, although bleeding wasn't a complication I had to deal with. I will research that more. If docs put her back on blood thinners we may need to adjust when you get to higher dosages, but starting doses will be fine.

If you want to make actual suppositories with a mold then use cocoa butter. I prefer capsules but use what works best for you.

 

[Pman1983]

Kristian, I think Sue did a pretty good job answering your questions. I'll focus on calculating dosages.

If you mix the 2 oils you have now equally you will get mixture that is 14% CBD and 35% THC, or 49% total cannabinoids. That's a little low so you can make first batch a little stronger with more CCO per batch.

Base unit for full batch is ml. I would go ahead and make full batch at 4 ml CCO to 17 ml olive oil, then add the additional 45 ml olive oil with 15 ml liquid lecithin, to make total 81 ml and fill the capsules, about 90 or so. Don't worry, you'll be able to use all of them.

Start by dosing rectally only, not vaginally, 1 capsule 5 times a day (30 minutes after taking the supplements).

After 4 days if she feels ready then increase to 1 rectally and 1 vaginally. I have no experience with vaginal suppositories. It's mucosal membrane so will be absorbed well, but may cause some euphoria. Theoretically it shouldn't. If it does and she's uncomfortable with it you can instead do 2 capsules rectally. With practice you can get them side by side just past the sphincter. Be careful not to push one up too far or she may get euphoria.

With the next batch you can increase both dosages at once or the one rectally first and other after you run out of lower dosage pills. Whatever she is comfortable with. By that point it will become intuitive. Just increase when ready.

Last thing on supplements. Chamomile tea has some apigenin but not much. I found 50 mg capsules online from Swansons. Alternatively you may find product called Amentomax where body building supplements are sold. It contains amentoflavone which is another good competitive inhibitor.

Relax (as much as you can right now) and know that just starting the process will start helping mom, and as you proceed it will quickly become much easier.


p.s.: When you use up 66% THC just continue same with 80% oil.

Hey KR

You say we should start with 4ml of CCO. 2 ml of the CBD and 2 ml of the THC. CBD is 27% and THC is 66%. How do you get to 49% of CCO? 14% and 35%. How do you calculate?

They can't stop her bleeding, so they are giving her blood. Maybe radiation if they can't stop the bleeding.

 

[SweetSue]

Hey KR

You say we should start with 4ml of CCO. 2 ml of the CBD and 2 ml of the THC. CBD is 27% and THC is 66%. How do you get to 49% of CCO? 14% and 35%. How do you calculate?

They can't stop her bleeding, so they are giving her blood. Maybe radiation if they can't stop the bleeding.

When you mix the oils in equal concentrations it essentially cuts each in half. That means you end up with a combined count of 49%. Our thoughts are with you and your mother Kristian.

 

[Radogast]

In my limitted experience, prescribing blood thinners is a combination of art and science.

When the doctors put my wife on blood thinners, the doctors had her blood tested every day. Once she stabilized, switched to warfarin, and stabilized again - then they went down to testing twice a week. There are outpatient clinics and in home nurses that specialize in managing blood thinner treatment.

- - - bottom line - - -

CBD may be a factor, but it is one of many factors, and blood thinner dosages need to be monitored anyway.