Jim Finnel
Fallen Cannabis Warrior & Ex News Moderator
The Effect of -9-Tetrahydrocannabinol on Herpes Simplex Virus Replication
R. Dean Blevins and Michael P. Dumic
Department of Biological Sciences Division of Health Sciences East Tennessee State University, Johnson City, Tenn. 37601, U.S.A.
Both herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) failed, in an identical fashion to replicate and produce extensive c.p.e. in human cell monolayer cultures which were exposed (8 h before infection, at infection, or 8 h p.i.) to various concentrations of -9-tetrahydrocannabinol. Similar results were obtained with a plaque assay utilizing confluent monkey cells. Possible mechanisms for this antiviral activity are discussed.
Source: The Effect of {Delta}-9-Tetrahydrocannabinol on Herpes Simplex Virus Replication -- Blevins and Dumic 49 (2): 427 -- Journal of General Virology
R. Dean Blevins and Michael P. Dumic
Department of Biological Sciences Division of Health Sciences East Tennessee State University, Johnson City, Tenn. 37601, U.S.A.
Both herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) failed, in an identical fashion to replicate and produce extensive c.p.e. in human cell monolayer cultures which were exposed (8 h before infection, at infection, or 8 h p.i.) to various concentrations of -9-tetrahydrocannabinol. Similar results were obtained with a plaque assay utilizing confluent monkey cells. Possible mechanisms for this antiviral activity are discussed.
Source: The Effect of {Delta}-9-Tetrahydrocannabinol on Herpes Simplex Virus Replication -- Blevins and Dumic 49 (2): 427 -- Journal of General Virology
