Hey ledbudz.
I will know the answer to this sometime this weekend. I currently have 2 of the DS200's over an aeroflo 30 I will say they cover the tubes perfectly!
I also have two of the DS400's that will FedEx says they are going to deliver tomorrow. I bought them to cover a 4x4 flood table. I'm confident I will get more than adequate coverage out of two of the DS400's over the table, but I will be able to verify once I get them hung up this weekend.
4 of the DS200's will more than cover your 4x5 no problems.
In terms of cost efficiency I wouldnt suggest 4 x 200's for 4x5.
20 more watts per hour vs 4 x 200's
$2200 pice tag for four (just using retail price tag for comparison) or basically $210 more than 2 x 400's
based on website, 2 x 400's can be hung to perfectly cover 4x5 with probably very nice third off effect too.