Peat Phreak
Well-Known Member
Results: A total of 1,657,800 hospitalizations were included. Of these, 13,095 (0.79%) were cannabis users and were likely to be male (65.6%) and Black (35%) compared to non-cannabis users.
After propensity score matching, the CUD group had lower mortality (2.9% compared to 5.5%, OR 0.43 [CI 0.34 – 0.55] p <0.001).
They also had lower rates of non-invasive (2.9% vs. 3.9 p <0.014), invasive mechanical ventilation (9.4% vs. 7.1%, p<0.001) and ECMO use (0.1 vs. 0.3 p <0.014).
They also had a lower rate of septic shock (3.1% vs. 4% p<0.03) and lesser GI bleeding (3.3% vs. 2.3% p<0.005) compared to no CUD.
The cost of hospitalization in the CUD group was significantly lower. There was no significant difference between the other complications assessed.
Conclusion: We found lower mortality rates, lesser need for mechanical ventilation, and reduced hospitalization expenses among cannabis users hospitalized with COVID-19. Further research is required to determine whether cannabinoid is a candidate for the treatment and prevention of COVID-19.
After propensity score matching, the CUD group had lower mortality (2.9% compared to 5.5%, OR 0.43 [CI 0.34 – 0.55] p <0.001).
They also had lower rates of non-invasive (2.9% vs. 3.9 p <0.014), invasive mechanical ventilation (9.4% vs. 7.1%, p<0.001) and ECMO use (0.1 vs. 0.3 p <0.014).
They also had a lower rate of septic shock (3.1% vs. 4% p<0.03) and lesser GI bleeding (3.3% vs. 2.3% p<0.005) compared to no CUD.
The cost of hospitalization in the CUD group was significantly lower. There was no significant difference between the other complications assessed.
Conclusion: We found lower mortality rates, lesser need for mechanical ventilation, and reduced hospitalization expenses among cannabis users hospitalized with COVID-19. Further research is required to determine whether cannabinoid is a candidate for the treatment and prevention of COVID-19.
Cannabis Use and COVID-19 Hospitalization Outcomes. A Retrospective Study
Background: In vitro studies have shown cannabinoids blocking SARS-CoV-2 cellular entry and affecting replication. There is a paucity of data assessing the
papers.ssrn.com
