anandamide

Spicy food and pot brownies sounds like a bad combo - I'm not judging - but a new study suggests they at least have one thing in common: they both calm the gut. According to a new study, hot peppers and marijuana contain chemicals that interact with the same receptors that line the stomach. The...

Mechanisms for Recycling and Biosynthesis of Endogenous Cannabinoids Anandamide and 2-Arachidonylglycerol Ekaterina A. Placzek, Yasuo Okamoto, Natsuo Ueda, and Eric L. Barker J Neurochem. 2008 November Abstract The mechanisms of endogenous cannabinoid biosynthesis are not completely...

Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats W-S Vanessa Ho and Sheila M Gardiner Br J Pharmacol. 2009 January Abstract Background and purpose The cardiovascular effects of cannabinoids can be influenced by anaesthesia and can differ...

Endocannabinoids and the haematological system M D Randall Br J Pharmacol. 2007 November Abstract Endocannabinoids are blood borne and may also be secreted by the endothelium. Accordingly, there has been interest in the interactions between (endo)cannabinoids and blood cells. There is...

Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats A J Wheal, T Bennett, M D Randall, and S M Gardiner Br J Pharmacol. 2007 November Abstract Background and purpose: In anaesthetized spontaneously hypertensive rats (SHR), there is evidence for up-regulation of...

Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB1 and TRPV1 receptors Maria Grazia Morgese, Tommaso Cassano, Vincenzo Cuomo, and Andrea Giuffrida Exp Neurol. 2007 November Abstract Levodopa is the most commonly prescribed drug for Parkinson's...

Endocannabinoid metabolism and uptake: novel targets for neuropathic and inflammatory pain M D Jhaveri, D Richardson, and V Chapman Br J Pharmacol. 2007 November Abstract Cannabinoid CB1 and CB2 receptors are located at key sites involved in the relaying and processing of noxious inputs. Both...

Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury Sándor Bátkai, Douglas Osei-Hyiaman, Hao Pan, Osama El-Assal, Mohanraj Rajesh, Partha Mukhopadhyay, Feng Hong, Judith Harvey-White, Anjum Jafri, György Haskó, John W. Huffman, Bin Gao, George Kunos, and...

Inhibition of Salivary Secretion by Activation of Cannabinoid Receptors Juan Pablo Prestifilippo*1, Javier Fernández-Solari*, Carolina de la Cal, María Iribarne, Angela M. Suburo, Valeria Rettori*, Samuel M. McCann* and Juan Carlos Elverdin Exp. Biol. Med. 2006 Abstract It is known...

Anandamide reduces infarct size in rat isolated hearts subjected to ischaemia—reperfusion by a novel cannabinoid mechanism Nichola J Underdown, C Robin Hiley, and William R Ford Br J Pharmacol. 2005 November Abstract 1. Although the endocannabinoids 2-arachidonoylglycerol (2-AG) and...

The effects of Δ9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide Saoirse E O'Sullivan, David A Kendall, and Michael D Randall Br J Pharmacol. 2005 June Abstract 1. Δ9-tetrahydrocannabinol (THC) produces varying effects in mesenteric...

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2 H A Patsos, D J Hicks, R R H Dobson, A Greenhough, N Woodman, J D Lane, A C Williams, and C Paraskeva Gut. 2005 December Abstract Background and aims...

The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2 H A Patsos, D J Hicks, R R H Dobson, A Greenhough, N Woodman, J D Lane, A C Williams, and C Paraskeva Gut. 2005 December Abstract Background and aims...

The cardiovascular actions of anandamide: more targets? Michael D Randall Br J Pharmacol. 2005 July The cardiovascular actions of endogenous cannabinoids such as anandamide are complex and confused (see Randall et al., 2004). Previously, in anaesthetised rats Malinowska and colleagues have...