SweetSue;3846753 said:Dave Groomer;3846594 said:Wait for one of the more experienced suppository users to chime in, but I believe most are making biobombs in #0 Gel caps. The carrier oil may vary combined with sunflower lecithin.
The gel caps hold a good dose and work magnificently as suppositories. They're easier to transport and use on the go too. I use olive oil for the capsule suppositories. I figure it's giving the cannabinoids a better chance, and olive oil can't be used in a form. Most of us now use capsules instead. I use FHO, others use biobombs. The concentration of cannabinoids depends on what you're treating.
As to the question of suppositories being effective for brain treatment, I offer KR's latest thoughts on the subject, pulled from Cajun's thread.
Originally posted by KingstonRabbi: "Second, I would take most of the cannabis oil as suppositories, mixed as biobombs. Gelcaps work very well as suppositories. This method has the high bioavailability an bypasses the liver so it can't metabolize THC. Some will still get to liver on 2nd pass through circulatory system, but competitive inhibition will continue to help here. It may seem odd to use a dosing method that's about as far from the brain as can be, but fact is that any medicine will have to travel in blood to get to brain. Properly inserted it will travel straight to heart, to the lungs and back, and then back out to body still untouched by liver, and much of that blood goes to the brain, so suppositories will still work well for your brother."
It's a common mistake to confuse lack of psychoactivity with effectiveness of THC once it's into the system. Over at Cajun's thread we're always telling people that our expectation, if you're dosing correctly and using methods of competitive inhibition, is that you won't be feeling intense psychoactivity. All cannabis is psychoactive. THC is simply moreso.
We simply have no firm data on what phytocannabinoids are doing in the body. I personally try to avoid making any limiting statements when I speak of the actions of the ECS and cannabinoid therapies. I believe much of the effectiveness of the regimen lies in the belief that it's going to work. Until I have evidence to the contrary I'm going with the successes we've documented in our own numbers to guide me.