Bioavailability Part A - The Perpetual Healing Garden - SweetSue's Joyful Return

SweetSue;2831738 said:

This is nothing more than a rewrite of Cajun's second post on his protocol thread. Here's the link to that if you'd care to check it out.

https://www.420magazine.com/community/threads/base-treatment-regimen-cancer.250499/post-2541622

The piece on Demethylation that precedes this is in my blog.

Thoughts on Demethylation and the Methylation Cycle

The next piece, on supercharging the CCO, should really be Part A, and I'll probably make that change before I compile it all into a unit.

It makes me nervous to put it out there like this. Writer's angst. The work is more important than my angst. I also like the idea that we all get to input our thoughts. It makes it more of a community project, and that appeals to me. What I'm looking for from you all is any areas that aren't clear to you or where you believe more info is needed to flesh it out.



BIOAVAIBILITY: Part A

This piece was written for cancer patients healing themselves with Concentrated Cannabis Oil. Those of us who smoke or vape or ingest recreationally don't tend to think of it as medicating ourselves, but the reality is you're doing just that. Your Endocannabinoid System takes those additional cannabinoids and heals your system too, you just weren't aware of it. These methods will increase the level of your buzz and get more working cannabinoids into your healing body.

Remember, it's a numbers game. You worked hard to produce oil loaded with numbers of cannabinoids, terpenes and other beneficial molecules. Now your challenge becomes getting the greatest number of those fighters into the system without being degraded, metabolized or eliminated. We want them active in the business of destroying cancer cells and assisting the immune system, and we want them there as long as possible before they get washed out.

Let's look at the practical steps you can take to help your body get the greatest benefit from your priceless medication. How can we increase bioavailability?

We've already covered demethylation, so you're already doing things like drinking lots of green tea, eating dark, dark chocolate, cinnamon, mangoes, etc. right? Good. It enhances your bioavailability. Cajun also recently shared that "other supplements like garlic, tumeric, vitamin D3, selenium, and especially fish-based Omega 3's, melatonin, ect. all contribute to the cco by synergy at least 50 fold."

Now it's time to dose.

Begin by eating about 30-40 minutes before you dose. Your main focus here is to get the liver occupied so that when you dose it's busy with the previous "meal" and more cannabinoids will slip by unmolested. Since the liver is the organ responsible for processing oils, a good option is a tablespoon full of coconut oil, which is easily absorbed by the small intestines and transported to the liver. You give the liver busy work and get the fabulous nutritional benefits of coconut oil all at once. Win/win.

**A cautionary note** Coconut oil is contraindicated as a prep for treating liver cancer. You want the coconut oil you introduce to have cannabinoids with it and you want them to get straight to the liver, so the coconut oil you use is the carrier oil for the CCO. With liver cancer the use of supplements is necessary to creatively inhibit the liver.

The enzymes in the liver that metabolize most of the THC are aggressive by nature, and it behooves you to get them busy before dosing and keep them busy as you dose. As it turns out, there are some plant molecules, apigenin and amentoflavone, that attract those very same enzymes, known as CYP2C9. So you're increasing your odds by flooding the field with distractions.

Aside from being "busy work" for the enzymes, apigenin and amentoflavone offer some interesting benefits. I found twenty different anti-cancer effects of apigenin alone, among them the ability to inhibit angiogenesis (growing new blood vessels so the cell can continue to live) and to promote cell apoptosis (suicide) and that wasn't an all-inclusive list. Cajun shared that his oncologist recommended he take 1.5 grams of apigenin daily. He admits to taking about 500 mg a day because he just got sick of the number of pills. I can certainly understand that.

You can get apigenin from food sources, (Ginko Biloba, for one) but at the recommended levels I think a source for tablets might be necessary. It's easy to find. You're treating cancer. Big guns are called for.

Amentoflavone has been used for centuries in Chinese medicine as an anti-cancer medication. I browsed through an interesting Chinese study of the anti-cancer mechanisms of amentoflavone in the destruction of typical breast cancer MCF-7 cells. To be blunt, the amentoflavone degraded the integrity of the mitochondrial wall until it shredded and the tumor cell died. Interestingly enough, this was one of the mechanisms used by cannabinoids to cause cell death. Fascinating. Amentoflavone has been used in traditional medicine as an antioxidant, vasorelaxant, anti-HIV and anti-angiogenesis agent. Again, not an inclusive list of the potential benefits.

Amentoflavone is also available as a supplement. One commonly used by weight lifters is Amentomax.

As Cajun so succinctly put it

cajuncelt;2541633 said:

"These molecules, as well as having additional benefits, will give the enzymes "busy work" allowing the cannabinoids greater opportunity to circulate, connect with and destroy mutated cells both in the liver and throughout the body"

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The Plan: 30-40 minutes before you dose

- a tablespoon of coconut oil (unless you're treating liver cancer)
- 80mg of apigenin
- 200mg of amentoflavone
- a cup of mango.

Now you're prepped for action. Have another cup of green tea.

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